CAD antibody (AA 780-809)
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- Target See all CAD Antibodies
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
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Binding Specificity
- AA 780-809
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CAD antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Predicted Reactivity
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-809 amino acids from the Central region of human CAD.
- Clone
- RB18384
- Isotype
- Ig Fraction
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anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibody
CAD Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 1650-1900) antibodyCAD Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 780-809) antibodyCAD Reactivity: Human WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (C-Term) antibodyCAD Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) antibodyCAD Reactivity: Human, Mouse IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (pThr456) antibodyCAD Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 205-222) antibodyCAD Reactivity: Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 2018-2067) antibodyCAD Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Zebrafish (Danio rerio), Bat, Hamster, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 1650-1700) antibodyCAD Reactivity: Human IHC, IHC (p), IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
- Alternative Name
- CAD (CAD Products)
- Synonyms
- Cpad antibody, AU018859 antibody, 2410008J01Rik antibody, cb456 antibody, wu:fc30c12 antibody, wu:fc33d01 antibody, wu:fc67g02 antibody, si:dkey-221h15.3 antibody, CAD antibody, xcad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, CAD antibody, Cad antibody, cad antibody
- Background
- The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
- Molecular Weight
- 242984
- Gene ID
- 790
- NCBI Accession
- NP_004332
- UniProt
- P27708
- Pathways
- Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
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