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TBC1D17 antibody

TBC1D17 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7119799
  • Target See all TBC1D17 Antibodies
    TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
    Reactivity
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    This TBC1D17 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    TBC1 domain family, member 17
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
    Alternative Name
    TBC1D17 (TBC1D17 Products)
    Synonyms
    BC017607 antibody, TBC1 domain family member 17 antibody, TBC1 domain family, member 17 antibody, TBC1D17 antibody, Tbc1d17 antibody
    Background
    Synonyms: Background:Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
    Molecular Weight
    73 kDa
    Gene ID
    79735
    UniProt
    Q9HA65
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