PRR5L antibody (AA 220-270)
PRR5L
Reactivity: Human, Mouse
WB, ELISA, IF, ICC
Host: Rabbit
Polyclonal
unconjugated
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- Target See all PRR5L Antibodies
- PRR5L (Proline Rich 5 Like (PRR5L))
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Binding Specificity
- AA 220-270
- Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRR5L antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
- Purification
- PRR5L Antibody is affinity chromatography purified via peptide column.
- Immunogen
- PRR5L antibody was raised against a 17 amino acid synthetic peptide near the center of human PRR5L. The immunogen is located within amino acids 220 - 270 of PRR5L.
- Isotype
- IgG
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anti-Proline Rich 5 Like (PRR5L) (Center) antibody
PRR5L Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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PRR5L antibody can be used for detection of PRR5L by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PRR5L Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- PRR5L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- PRR5L (Proline Rich 5 Like (PRR5L))
- Alternative Name
- PRR5L (PRR5L Products)
- Synonyms
- PROTOR2 antibody, 2600010E01Rik antibody, 4833411O04Rik antibody, Protor-2 antibody, Protor2 antibody, RGD1309969 antibody, PRR5L antibody, FLJ14213 antibody, proline rich 5 like antibody, PRR5L antibody, Prr5l antibody, prr5l antibody
- Background
- PRR5L Antibody: Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
- Gene ID
- 79899
- NCBI Accession
- NP_001153639
- UniProt
- Q6MZQ0
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