WNT4 antibody (Center)
(1 reference)-
- Target See all WNT4 Antibodies
- WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WNT4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Characteristics
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Rabbit Polyclonal antibody to WNT4 (protein Wnt-4)
WNT4 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human WNT4. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 211-239) antibody
WNT4 Reactivity: Human, Mouse, Rat WB, IHC (p), FACS Host: Rabbit Polyclonal RB19965 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 23-351) antibodyWNT4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 26-351) antibodyWNT4 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 201-300) antibodyWNT4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (Internal Region) antibodyVerified WNT4 Reactivity: Human WB, ELISA, IF Host: Goat Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 242-269) antibodyWNT4 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 211-239) antibodyWNT4 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 242-269), (C-Term) antibodyWNT4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB19966 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 1-351) antibodyWNT4 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 4 (WNT4) (AA 250-351) antibody (HRP)WNT4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal HRP
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- Application Notes
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*
- Comment
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Positive Control: 293T , HepG2 , WNT4 transfected 293T lysate , V5-human Wnt4-transfected 293T
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.78 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Effect of Huayu Tongluo Herbs on Reduction of Proteinuria via Inhibition of Wnt/β-Catenin Signaling Pathway in Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 3054145, (2017) (PubMed).
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: "Effect of Huayu Tongluo Herbs on Reduction of Proteinuria via Inhibition of Wnt/β-Catenin Signaling Pathway in Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 3054145, (2017) (PubMed).
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- Target
- WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))
- Alternative Name
- WNT4 (WNT4 Products)
- Synonyms
- CG4698 antibody, DWnt-4 antibody, DWnt4 antibody, Dm DWnt4 antibody, Dmel\\CG4698 antibody, Dwnt4 antibody, Wnt antibody, Wnt-4 antibody, anon-EST:Liang-2.4 antibody, clone 2.4 antibody, wnt-4 antibody, wnt4 antibody, SERKAL antibody, WNT-4 antibody, Xwnt4 antibody, xwnt-4 antibody, zgc:136737 antibody, Wnt family member 4 antibody, Wnt oncogene analog 4 antibody, wingless-type MMTV integration site family, member 4 antibody, wingless-type MMTV integration site family member 4 S homeolog antibody, wingless-type MMTV integration site family, member 4a antibody, WNT4 antibody, Wnt4 antibody, wnt4.S antibody, wnt4a antibody
- Background
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98 % amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.
Cellular Localization: Secreted , extracellular space , extracellular matrix - Molecular Weight
- 39 kDa
- Gene ID
- 54361
- Pathways
- WNT Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cell-Cell Junction Organization, Tube Formation
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