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WNT4 Products

(Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008].

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Featured WNT4 Categories

WNT4 Antibodies

High quality antibodies with extensive validation data.

WNT4 ELISA Kits

Reliable ELISA kits for a wide range of species.

WNT4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WNT4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (1)
  • (5)
Cat. No. ABIN2854927
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3029632
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (4)
Cat. No. ABIN7166300
Quantity 100 μg
Datasheet Datasheet

Recommended WNT4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971190
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971191
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960547
Quantity 96 tests
Datasheet Datasheet

Recommended WNT4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075629
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710626
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7090611
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our WNT4 products

Zhang, Mehmood, Jiang, Yao, Iqbal, Waqas, Rehman, Li, Shen, Li: "Effect of tetramethyl thiuram disulfide (thiram) in relation to tibial dyschondroplasia in chickens." in: Environmental science and pollution research international, Vol. 25, Issue 28, pp. 28264-28274, (2019) (PubMed).

Chen, Chen, Wallace, Chen, Yang, Sung, Chiang, Chen, Chua, Yip, Cheng: "Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome." in: American journal of translational research, Vol. 9, Issue 2, pp. 214-229, (2017) (PubMed).

Chang, Hsu, Yang, Sung, Chen, Huang, Kao, Chen, Chen, Chiang, Yip, Lee: "Enhanced protection against renal ischemia-reperfusion injury with combined melatonin and exendin-4 in a rodent model." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1588-602, (2017) (PubMed).

Bai, Huo, Chen, Guo, Xu, Fang, Zhang, Zhang: "Effect of Huayu Tongluo Herbs on Reduction of Proteinuria via Inhibition of Wnt/β-Catenin Signaling Pathway in Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 3054145, (2017) (PubMed).

Hua, Xu, He, Jiang, Ye, Pan: "Wnt4/?-catenin signaling pathway modulates balloon-injured carotid artery restenosis via disheveled-1." in: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 8421-31, (2015) (PubMed).

Chopra, Kumar, Rangarajan, Kondaiah: "Context dependent non canonical WNT signaling mediates activation of fibroblasts by transforming growth factor-β." in: Experimental cell research, Vol. 334, Issue 2, pp. 246-59, (2015) (PubMed).

Lin, Jan, Kuo: "Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine." in: Molecular pharmaceutics, Vol. 12, Issue 8, pp. 2858-68, (2015) (PubMed).

Hua, He, Xu, Jiang, Ye, Pan: "Emodin prevents intima thickness via Wnt4/Dvl-1/β-catenin signaling pathway mediated by miR-126 in balloon-injured carotid artery rats." in: Experimental & molecular medicine, Vol. 47, pp. e170, (2015) (PubMed).

Fang, Zeng, Wang, Liu, Xu, Dai, Zhao, Zhang, Liang, Chen, Shi, Zhang, Wang, Qiao, Shi: "Estimated diversity of messenger RNAs in each murine spermatozoa and their potential function during early zygotic development." in: Biology of reproduction, Vol. 90, Issue 5, pp. 94, (2014) (PubMed).

Ring, Neth, Weber, Steffens, Faussner et al.: "β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 ..." in: Cellular signalling, Vol. 26, Issue 2, pp. 260-7, (2013) (PubMed).

Synonyms and alternative names related to WNT4

Wnt family member 4 (WNT4), Wnt oncogene analog 4 (Wnt4), wingless-type MMTV integration site family, member 4 (Wnt4), Wnt family member 4 (Wnt4), wingless-type MMTV integration site family member 4 S homeolog (wnt4.S), wingless-type MMTV integration site family, member 4a (wnt4a), anon-EST:Liang-2.4, CG4698, clone 2.4, Dm DWnt4, Dmel\\CG4698, DWnt-4, DWnt4, Dwnt4, SERKAL, Wnt, Wnt-4, wnt-4, WNT-4, wnt4, xwnt-4, Xwnt4, zgc:136737

Protein level used designations for WNT4

  • CG4698-PA
  • CG4698-PB
  • Wnt4-PA
  • Wnt4-PB
  • wingless-type MMTV integration site family, member 4
  • protein Wnt-4
  • signal molecule
  • wingless-related MMTV integration site 4
  • (Xwnt-4)
  • Wnt-4 protein
  • protein Wnt-4a
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