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SIGLEC5 antibody (AA 17-230)

SIGLEC5 Reactivity: Human WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 3F5A3 unconjugated
Catalog No. ABIN7193301
  • Target See all SIGLEC5 Antibodies
    SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
    Binding Specificity
    • 12
    • 9
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    AA 17-230
    Reactivity
    • 64
    • 28
    • 4
    Human
    Host
    • 59
    • 5
    • 3
    Mouse
    Clonality
    • 59
    • 8
    Monoclonal
    Conjugate
    • 24
    • 11
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC5 antibody is un-conjugated
    Application
    • 54
    • 34
    • 15
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. coli.
    Clone
    3F5A3
    Isotype
    IgG2a
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
    Alternative Name
    CD170 (SIGLEC5 Products)
    Synonyms
    CD170 antibody, CD33L2 antibody, OB-BP2 antibody, OBBP2 antibody, SIGLEC-5 antibody, sialic acid binding Ig like lectin 5 antibody, sialic acid-binding Ig-like lectin 5 antibody, sialic acid binding Ig-like lectin 5 antibody, SIGLEC5 antibody, LOC100597560 antibody, Siglec5 antibody
    Background

    Description: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

    Aliases: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5

    Molecular Weight
    60.7 kDa
    Gene ID
    8778
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