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PAN2 antibody (AA 628-908)

PAN2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7162471
  • Target See all PAN2 Antibodies
    PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 628-908
    Reactivity
    • 25
    • 2
    • 1
    Human
    Host
    • 24
    • 1
    Rabbit
    Clonality
    • 24
    • 1
    Polyclonal
    Conjugate
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    This PAN2 antibody is un-conjugated
    Application
    • 21
    • 17
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human PAB-dependent poly(A)-specific ribonuclease subunit PAN2 protein (628-908AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
    Alternative Name
    PAN2 (PAN2 Products)
    Synonyms
    USP52 antibody, 1200014O24Rik antibody, AI047843 antibody, AW742773 antibody, Usp52 antibody, mKIAA0710 antibody, PAN2 antibody, pan2 antibody, PAN2 poly(A) specific ribonuclease subunit antibody, PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) antibody, PAN2 poly(A) specific ribonuclease subunit S homeolog antibody, PAN2 antibody, Pan2 antibody, pan2.S antibody
    Background

    Background: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3\\\'-5\\\' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5\\\'-3\\\' exonucleolytic degradation by XRN1.

    Aliases: hPan2 antibody, Inactive ubiquitin carboxyl terminal hydrolase 52 antibody, Inactive ubiquitin carboxyl-terminal hydrolase 52 antibody, KIAA0710 antibody, PAB dependent poly(A) specific ribonuclease subunit 2 antibody, PAB-dependent poly(A)-specific ribonuclease subunit 2 antibody, PABP dependent poly(A) nuclease 2 antibody, PAN 2 antibody, PAN2 antibody, PAN2 homolog PABP1 dependent poly A specific ribonuclease subunit antibody, PAN2 poly(A) specific ribonuclease subunit homolog antibody, PAN2 polyA specific ribonuclease subunit homolog antibody, PAN2_HUMAN antibody, Ubiquitin specific peptidase 52 antibody, Ubiquitin specific protease 52 antibody, USP 52 antibody, USP52 antibody

    UniProt
    Q504Q3
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