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On www.antibodies-online.com are 36 Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) ELISA Kits from 10 different suppliers available. Additionally we are shipping ERN1 Antibodies (210) and ERN1 Proteins (15) and many more products for this protein. A total of 275 ERN1 products are currently listed.
Synonyms:
9030414B18Rik, AI225830, C85377, Ern1, hIRE1p, IRE1, IRE1a, Ire1alpha, Ire1b, IRE1P, RGD1559716
list all ELISA KIts Gene Name GeneID UniProt
ERN1 78943 Q9EQY0
ERN1 2081 O75460
ERN1 498013  

ERN1 (ERN1) ELISA Kits by Reactivity

More ELISA Kits for ERN1 Interaction Partners

Mouse (Murine) Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) interaction partners

  1. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

  2. defective autophagy in intestinal epithelial cells (IECs) may predispose to Crohn's disease ileitis via impaired clearance of IRE1alpha aggregates during ER stress at this site.

  3. The findings indicate that IRE1-XBP1 (show XBP1 ELISA Kits) downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  4. the ABL (show ABL1 ELISA Kits) family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  5. We reveal distinct binding affinities between the binary and ternary complexes thus formed, that suggest a preference for the PERK (show EIF2AK3 ELISA Kits) signaling branch under stress, and a predilection for the GRP78 (show HSPA5 ELISA Kits)-UPR sensor complex formation upon stressor removal. These results imply a gated UPR mechanism that tunes the overall cellular behavior to the accumulation of unfolded proteins.

  6. Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs.

  7. Ire1alpha-Xbp1s and associated molecular targets link ER stress in arcuate Pomc (show POMC ELISA Kits) neurons to aspects of normal energy and glucose homeostasis.

  8. heat stress simultaneously activates both the unfolded protein response (UPR) and autophagy, followed by the activation of a negative feedback system in UPR by modulating the responses related to the IRE1alpha-XBP-1 (show XBP1 ELISA Kits) axis.

  9. this study shows that IRE1alpha is a critical switch governing M1-M2 macrophage polarization and energy balance in obesity

  10. Findings indicate that PERK (show EIF2AK3 ELISA Kits) kinase-activating transcription factor 4 (ATF4 (show ATF4 ELISA Kits)) pathway affected the efficiency of X-box binding protein 1 (XBP1 (show XBP1 ELISA Kits)) mRNA splicing by regulating inositol-requiring enzyme 1alpha (IRE1alpha) expression.

Human Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) interaction partners

  1. The unfolded protein response reduces glucose metabolism via IRE1 signaling.

  2. Results of this investigation demonstrate that inhibition of IRE1 signaling enzyme function affects the expression of NRIP1 (show NRIP1 ELISA Kits), EBBP (show TRIM16 ELISA Kits), ESRRA (show ESRRA ELISA Kits), E2IG5 (show FAM162A ELISA Kits), PGRMC2 (show PGRMC2 ELISA Kits), and SLC39A6 (show SLC39A6 ELISA Kits) genes in U87 glioma cells in gene specific manner and these changes possibly contribute to the suppression of the cell proliferation. Most of these genes are regulated by hypoxia and preferentially through IRE1 signaling pathway of endoplasmic reticulum stress

  3. IRE1alpha was shown to cleave miR (show MLXIP ELISA Kits)-150 and thereby to release the suppressive effect that miR (show MLXIP ELISA Kits)-150 exerted on alphaSMA (show ACTA2 ELISA Kits) expression through c-Myb (show MYB ELISA Kits). Inhibition of IRE1alpha was also demonstrated to block endoplasmic reticulum expansion through an XBP-1 (show XBP1 ELISA Kits)-dependent pathway.

  4. IRE-1 has an ancient function as a cytoplasmic sentinel that activates p38 (show CRK ELISA Kits) and SKN-1(Nrf2 (show GABPA ELISA Kits)). csteine modifications induced by ROS (show ROS1 ELISA Kits) signals can direct proteins to adopt unexpected functions and may coordinate many cellular processes.

  5. The findings indicate that IRE1-XBP1 (show XBP1 ELISA Kits) downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  6. Western blot analysis of subcutaneously implanted AsPC-1 and BxPC-3 tumors as well as orthotopically implanted Panc-1 tumors demonstrated upregulation of BIP (show GDF10 ELISA Kits), CHOP (show DDIT3 ELISA Kits), and IRE1alpha expression in the tumor lysates from penfluridol-treated mice as compared to tumors from control mice

  7. the ABL (show ABL1 ELISA Kits) family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  8. Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK (show EIF2AK3 ELISA Kits) and IRE1 signalings

  9. IRE1 is involved in multivesicular body information during endoplasmic reticulum stress.

  10. Comparison of this structure with other existing structures of IRE1alpha and integration of our extensive structure activity relationship (SAR (show SARDH ELISA Kits)) data has led us to formulate a model to rationalize how ATP-binding site ligands are able to control the IRE1alpha oligomeric state and subsequent RNase domain activity

ERN1 Antigen Profile

Antigen Summary

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Alternative names and synonyms associated with ERN1

  • endoplasmic reticulum (ER) to nucleus signalling 1 (Ern1) Elisa Kit
  • endoplasmic reticulum (ER) to nucleus signalling 2 (Ern2) Elisa Kit
  • endoplasmic reticulum to nucleus signaling 1 (ERN1) Elisa Kit
  • endoplasmic reticulum to nucleus signaling 1 (Ern1) Elisa Kit
  • endoplasmic reticulum to nucleus signalling 1 (LOC100357346) Elisa Kit
  • 9030414B18Rik Elisa Kit
  • AI225830 Elisa Kit
  • C85377 Elisa Kit
  • Ern1 Elisa Kit
  • hIRE1p Elisa Kit
  • IRE1 Elisa Kit
  • IRE1a Elisa Kit
  • Ire1alpha Elisa Kit
  • Ire1b Elisa Kit
  • IRE1P Elisa Kit
  • RGD1559716 Elisa Kit

Protein level used designations for ERN1

endoplasmic reticulum-to-nucleus signaling 1 , inositol-requiring 1 alpha , inositol-requiring protein 1 , ire1-alpha , serine/threonine-protein kinase/endoribonuclease IRE1 , endoplasmic reticulum-to-nucleus signaling 2 , inositol-requiring 1 (Yeast homologue) , inositol-requiring 1 beta , inositol-requiring protein 2 , ire1-beta , mIre1 , serine/threonine-protein kinase/endoribonuclease IRE2 , ER to nucleus signalling 1 , inositol-requiring 1 , inositol-requiring enzyme 1 , protein kinase/endoribonuclease , endoplasmic reticulum (ER) to nucleus signalling 1 , endoplasmic reticulum to nucleus signalling 1

GENE ID SPECIES
78943 Mus musculus
26918 Mus musculus
2081 Homo sapiens
498013 Rattus norvegicus
100733391 Cavia porcellus
100510978 Sus scrofa
610766 Canis lupus familiaris
524719 Bos taurus
771230 Gallus gallus
101102746 Ovis aries
100357346 Oryctolagus cuniculus
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