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Ki-1/57 may be involved in translational regulation
Ki-1/57 is localized to several subnuclear domains, all of which have been described to splicing and other RNA processing events.
interacts with the C-terminal region of the human chromatin-remodeling factor (show ASH1L Proteins) CHD-3 (show CHD3 Proteins)
association of Ki-1/57 with the RACK1/PKC pathway and may be important for the regulation of its cellular functions
MEF2C (show MEF2C Proteins) DNA-binding activity is inhibited through its interaction with Ki-1/57.
Has two conserved Gly/Arg-rich motif clusters (RGG/RXR box, where X is any amino acid) that may be substrates for arginine-methylation by PRMT1 (show PRMT1 Proteins).
Data suggest that Ki-1/57 has characteristics of an intrinsically unstructured protein, which may explain its functional plasticity.
Findings suggest that Ki-1/57 is probably involved in cellular events related to RNA functions, such as pre-mRNA splicing.
Transcriptional activator (By similarity).
hyaluronan binding protein 4
, intracellular hyaluronan-binding protein 4
, chromodomain helicase DNA binding protein 3 interacting protein
, intracellular antigen detected by monoclonal antibody Ki-1
, ki-1/57 intracellular antigen
, hyaluronic acid binding protein 4
, intracellular hyaluronan-binding protein p57
, hyaluronic acid-binding protein 4 (intracellular)