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Osteomodulin (OMD) directly binds to type 1 collagen. OMD suppresses formation of collagen fibrils.
Osteomodulin, osteoglycin (show OGN ELISA Kits), and asporin (show ASPN ELISA Kits) appear to be distinctly regulated in osteoarthritis labrum compared to OA cartilage.
TGF beta 1 (show TGFB1 ELISA Kits) signaling and stimulation of osteoadherin in human pulpal fibroblasts and in early secretory and mature odontoblasts
tyrosine sulfate-rich domains of the LRR proteins fibromodulin (show FMOD ELISA Kits) and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors
found transforming growth factor beta1 to down regulate OSAD, while bone morphogenetic protein 2 (show BMP2 ELISA Kits) up regulates OSAD
OSAD overexpression enhanced the differentiation and maturation of osteoblasts in vitro.
May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)- integrin (By similarity).
, KSPG osteomodulin
, keratan sulfate proteoglycan osteomodulin
, osteoadherin proteoglycan