Browse our PAPSS2 Proteins (PAPSS2)

Full name:
3'-phosphoadenosine 5'-phosphosulfate Synthase 2 Proteins (PAPSS2)
On are 5 3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2) Proteins from 3 different suppliers available. Additionally we are shipping PAPSS2 Antibodies (68) and many more products for this protein. A total of 80 PAPSS2 products are currently listed.
1810018P12Rik, AI159688, Atpsk2, AtpsU2, BCYM4, bm, id:ibd2761, Papss1, papss2, sb:cb868, Sk2, wu:fb12e05, zgc:55851, zgc:85655
list all proteins Gene Name GeneID UniProt
PAPSS2 9060 O95340
PAPSS2 23972 O88428
Rat PAPSS2 PAPSS2 294103  

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PAPSS2 Proteins (PAPSS2) by Origin

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Human 3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2) interaction partners

  1. In an Amish population, using expression profiling of genes within regions identified by a meta-analysis GWAS of survival to age 90, we localized PAPSS2 as a candidate gene for extended life span. These results provide novel evidence for genetic loci implicated in longevity and incorporate gene expression results from a unique population to locate positional candidates.

  2. Silencing of SULT1A1 (show SULT1A1 Proteins) and PAPSS2 led to a significant decrease in aristolactam-DNA levels in both cell lines following exposure to AA-I, indicating the critical role for sulfonation in the activation of AA-I in vivo Since HK-2 (show HK2 Proteins) cells proved relatively resistant to knockdown with siRNAs

  3. Our results indicate that FGFR2 (show FGFR2 Proteins) and PAPSS2 may play an important role in the regulation of magnesium homeostasis in children of European-American ancestry.

  4. Results suggest that the loss of the susceptible region on chromosome 10q, which implicates PTEN, FAS (show FAS PLURAL_@39934@) and PAPSS2 may serve as genetic predictors of PSA (show PLAG1 PLURAL_@39934@) recurrence after radical prostatectomy.

  5. Direct in vivo evidence for the significant functional impact of mutant PAPSS2 on DHEA sulfation and androgen activation.

  6. PAPSS2-brachyolmia includes phenotypes of the conventional clinical concept of brachyolmia, the Hobaek and Toledo types, and is associated with abnormal androgen metabolism.

  7. Papss2 expression is reduced in articular cartilage following transforming growth factor-beta administration.

  8. PAPSS2 is the disease gene for an autosomal recessive brachyolmia.

  9. Unusual localisation signals of both PAPS (show PAPSS1 Proteins) synthase isoforms, are described.

  10. Thirty-seven novel SNPs in the PAPSS2 gene and in two intergenic regions on chromosomes 2q33.1 and 18p11.32 were associated with exercise participation.

Mouse (Murine) 3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2) interaction partners

  1. Genetic variants in SULT2A1 (show SULT2A1 Proteins), PAPSS2, and STS (show STS Proteins) do not predispose to polycystic ovary syndrome.

  2. The results suggest that PAPSS2 might regulate osteoblast ALP (show CCL21A Proteins) activity and cell mineralization, probably through Smads signal pathways.

  3. hypertrophic chondrocytes show a dramatic down-regulation of Papss2 mRNA expression, indicating an important role of the gene product for cartilage growth and development in the embryo

PAPSS2 Protein Profile

Protein Summary

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Alternative names and synonyms associated with PAPSS2

  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (LOC100230837)
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2)
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (LOAG_05620)
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (papss2)
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 2b (papss2b)
  • 1810018P12Rik protein
  • AI159688 protein
  • Atpsk2 protein
  • AtpsU2 protein
  • BCYM4 protein
  • bm protein
  • id:ibd2761 protein
  • Papss1 protein
  • papss2 protein
  • sb:cb868 protein
  • Sk2 protein
  • wu:fb12e05 protein
  • zgc:55851 protein
  • zgc:85655 protein

Protein level used designations for PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2 , bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 , adenosine 5'-phosphosulfate kinase/ATP sulfurylase 2 , bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2-like , 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2 , ATP sulfurylase/APS kinase 2 , ATP sulfurylase/adenosine 5'-phosphosulfate kinase , PAPS synthase 2 , PAPS synthetase 2 , SK 2 , bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 , PAPSS 2 , brachymorphic , sulfurylase kinase 2

100071740 Equus caballus
466140 Pan troglodytes
704688 Macaca mulatta
100230837 Taeniopygia guttata
100379231 Cavia porcellus
100392480 Callithrix jacchus
100443902 Pongo abelii
9943030 Loa loa
100540947 Meleagris gallopavo
100555422 Anolis carolinensis
100603353 Nomascus leucogenys
9060 Homo sapiens
23972 Mus musculus
294103 Rattus norvegicus
398910 Xenopus laevis
423678 Gallus gallus
486463 Canis lupus familiaris
536409 Bos taurus
80939 Danio rerio
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