You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Potassium Channel Tetramerisation Domain Containing 11 Proteins (KCTD11)

Full name:
Potassium Channel Tetramerisation Domain Containing 11 Proteins (KCTD11)
On www.antibodies-online.com are 6 Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) Proteins from 4 different suppliers available. Additionally we are shipping Potassium Channel Tetramerisation Domain Containing 11 Antibodies (34) and Potassium Channel Tetramerisation Domain Containing 11 Kits (5) and many more products for this protein. A total of 52 Potassium Channel Tetramerisation Domain Containing 11 products are currently listed.
Synonyms:
AF465352, C17orf36, KCASH1, KCTD11, REN, REN/KCTD11
list all proteins Gene Name GeneID UniProt
KCTD11 216858 Q8K485
KCTD11 147040 Q693B1
Rat KCTD11 KCTD11 363634  

Show all synonyms

Potassium Channel Tetramerisation Domain Containing 11 Proteins (KCTD11) by Origin

Select your origin of interest

Top referenced Potassium Channel Tetramerisation Domain Containing 11 Proteins

  1. Human KCTD11 Protein expressed in Escherichia coli (E. coli) - ABIN1098777 : Di Marcotullio, Ferretti, De Smaele, Argenti, Mincione, Zazzeroni, Gallo, Masuelli, Napolitano, Maroder, Modesti, Giangaspero, Screpanti, Alesse, Gulino: REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 references for ABIN1098777

More Proteins for Potassium Channel Tetramerisation Domain Containing 11 Interaction Partners

Mouse (Murine) Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) interaction partners

  1. Results show negative regulation of HDAC1 (show HDAC1 Proteins) by a Cul3 (show CUL3 Proteins)-REN E3 ubiquitin ligase (show MUL1 Proteins) complex.

  2. REN is upregulated by neurogenic signals (retinoic acid, EGF, and NGF) in embryonal stem (ES) cells and neural progenitor cell lines in association with neurotypic differentiation.

  3. REN protein enhances caspase-3 (show CASP3 Proteins) activation and antagonizes the Shh (show SHH Proteins) pathway suggesting that this gene may represent a restraint of Shh (show SHH Proteins) signaling.

Human Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) interaction partners

  1. Our study demonstrates and supports that KCTD11, as well as negatively regulated downstream effectors belonging to Hh signaling, plays a role in prostate cancer pathogenesis.

  2. findings identify KCTD11 as a widely down-regulated gene in human cancers, and provide a basis to understand how its expression might be deregulated in tumor cells

  3. Results identify REN(KCTD11) as a suppressor of Hedgehog (show SHH Proteins) signaling and suggest that its inactivation might lead to a deregulation of the tumor-promoting Hedgehog (show SHH Proteins) pathway in medulloblastoma.

Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) Protein Profile

Protein Summary

Plays a role as a marker and a regulator of neuronal differentiation\; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and nerve growth factor/NGFB. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. May play a role as a tumor repressor and functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1 (By similarity).

Alternative names and synonyms associated with Potassium Channel Tetramerisation Domain Containing 11 (KCTD11)

  • potassium channel tetramerisation domain containing 11 (KCTD11)
  • potassium channel tetramerisation domain containing 11 (Kctd11)
  • potassium channel tetramerization domain containing 11 (KCTD11)
  • potassium channel tetramerization domain containing 11 (Kctd11)
  • AF465352 protein
  • C17orf36 protein
  • KCASH1 protein
  • KCTD11 protein
  • REN protein
  • REN/KCTD11 protein

Protein level used designations for KCTD11

potassium channel tetramerisation domain containing 11 , BTB/POZ domain-containing protein KCTD11 , retinoic acid, EGF, and NGF upregulated , retinoic acid, EGF, NGF induced gene protein , retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11

GENE ID SPECIES
468442 Pan troglodytes
539167 Bos taurus
216858 Mus musculus
607761 Canis lupus familiaris
147040 Homo sapiens
363634 Rattus norvegicus
Selected quality suppliers for Potassium Channel Tetramerisation Domain Containing 11 Proteins (KCTD11)
Did you look for something else?