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Human Monoclonal HRAS1 Primary Antibody for ELISA, WB - ABIN2473919
Baron: Start and run a medical dining club. in BMJ (Clinical research ed.) 1990
Show all 2 Pubmed References
High HRAS (show HRAS Antibodies) expression is associated with hepatocarcinogenesis.
p21 (show D4S234E Antibodies)-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths, identifies a novel, significant antagonism between p21 (show D4S234E Antibodies) and ras(Ha)/ROCK2 (show ROCK2 Antibodies)/NF-kappaB (show NFKB1 Antibodies) signalling in skin carcinogenesis.these data show that ROCK2 (show ROCK2 Antibodies) activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 (show TP53 Antibodies) loss and novel NF-kappaB (show NFKB1 Antibodies) expression
this study shows that retinoic acid stabilizes HRas (show HRAS Antibodies) protein during neurogenesis.
we provide genetic evidence that the wild-type H-Ras and K-Ras proteins are bioequivalent in spite of their different structural and biological properties
loss of one allele of Hras (show HRAS Antibodies) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (show HRAS Antibodies) allele. However, loss of one or both alleles of Nras (show NRAS Antibodies) failed to alter tumor burden, either in the absence or presence of Hras (show HRAS Antibodies), after exposure to urethane.
H-ras (show HRAS Antibodies) isoform mediates protection against pressure overload-induced cardiac dysfunction in part through activation of AKT (show AKT1 Antibodies)/PI3K signaling pathway.
The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to de-repress c-Myc (show MYC Antibodies) expression and to promote cell transformation assisted by the constitutively active H-Ras (show HRAS Antibodies).
these contrasting signatures precisely match those proposed to confer bias toward Hras (show HRAS Antibodies)(CAA61CTA) versus Braf (show BRAF Antibodies)(GTG636GAG) mutations in the original tumor sets. Our findings highlight a novel mechanism whereby exposure history acts through strand-biased mutagenesis to specify activation of preferred oncogenes
The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 (show BCL2 Antibodies) suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes
Ras (G12V)-induced cyclin D1 (show CCND1 Antibodies) protein synthesis was markedly suppressed by the knockdown of IL-33 (show IL33 Antibodies).
Suggest that loss of RASSF7 expression results in apoptosis in nucleus pulposus cells in human intervertebral disc degeneration.
truncated RASSF7 could act as an oncogene (show RAB1A Antibodies) in a small subset of tumours where it is mutated in this way.
The RASSF gene family members RASSF5 (show RASSF5 Antibodies), RASSF6 (show RASSF6 Antibodies) and RASSF7 show frequent DNA methylation (show HELLS Antibodies) in neuroblastoma (show ARHGEF16 Antibodies).
RASSF7 acts in concert with N-Ras (show NRAS Antibodies) to constitute a stress-sensitive temporary mechanism of apoptotic regulation.
RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B (show AURKB Antibodies) activation and chromosomal congression during mitosis.
"rare" alleles of HRas1 minisatellite are associated with increased risk of papillary thyroid cancer formation in children and adolescents after Chernobyl accident
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
, neuroblastoma ras oncogene
, transforming protein N-Ras
, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
, GTPase HRas
, transforming protein p21
, v-Ha-ras Harvey rat sarcoma viral oncogene-like protein
, H-ras 1 protein
, c-Ha-ras p21 protein
, c-Ha-ras transgene
, transforming protein P21
, HRAS1-related cluster protein 1
, HRAS1-related cluster-1
, Ras association (RalGDS/AF-6) domain family 7
, ras association domain-containing protein 7