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Human BMP10 Protein expressed in HEK-293 - ABIN2666462
Huang, Elicker, Bowens, Liu, Cheng, Cappola, Zhu, Parmacek: Myocardin regulates BMP10 expression and is required for heart development. in The Journal of clinical investigation 2012
Show all 4 references for ABIN2666462
Circulating Bmp10 acts via Alk1 (show ACVRL1 Proteins) to limit endothelial cell number in nascent arteries.
Forced expression of BMP10 in gastric cancer (GC) cells inhibited its growth and migration, while knocking down the expression of BMP10 in GC cells promoted cell growth, migration, and metastasis.
The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells.
BMP10, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP10 signaling may play a pivotal role in disease development.
Low expression of bone morphogenetic protein-10 is associated with urothelial cancer of the bladder.
Soluble endoglin (show ENG Proteins) specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
Furin (show FURIN Proteins) is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.
Bone morphogenetic protein-10 (BMP-10) may function as a tumor suppressor in breast cancer.
Hypertension induced expression of prohypertrophic BMP10, and the hypertrophic effect of BMP10 was modulated, at least in part, by its binding to Tcap (show TCAP Proteins) at the Z disc.
Describes the cloning and expression of murine BMP-10.
result was supported by the identification of the regulation by BMP9 (show GDF2 Proteins) and BMP10 of several genes known to be involved in this process
BMP10 has an exclusive function in cardiac development, which cannot be substituted by BMP9 (show GDF2 Proteins).
Myocardin transactivated Bmp10 via binding of a serum response factor-myocardin complex to a nonconsensus CArG element in the Bmp10 promoter. A myocardin/BMP10 signaling pathway regulates cardiomyocyte proliferation & apoptosis in embryonic heart.
BMP9 (show GDF2 Proteins) and BMP10 are important in postnatal vascular remodeling of the retina and BMP10 can substitute for BMP9 (show GDF2 Proteins).
the BMP10-Tbx20 (show TBX20 Proteins) signaling cascade is important for ventricular wall development and maturation.
Results describe an essential role of bone morphogenetic protein 10 in regulating cardiac growth and chamber maturation.
bone morphogenetic protein 10 in myocardium has a role in cardiac postnatal hypertrophic growth
The protein encoded by this gene is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases.
bone morphogenetic protein 10
, bone morphogenetic protein 10-like
, bone morphogenetic protein-10