Browse our Activin A Receptor, Type IIB (ACVR2B) ELISA Kits

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Activin A Receptor, Type IIB ELISA Kits (ACVR2B)
On www.antibodies-online.com are 2 Activin A Receptor, Type IIB (ACVR2B) ELISA Kits from 2 different suppliers available. Additionally we are shipping Activin A Receptor, Type IIB Antibodies (137) and Activin A Receptor, Type IIB Proteins (34) and many more products for this protein. A total of 191 Activin A Receptor, Type IIB products are currently listed.
Synonyms:
ActR-IIB, actr2b, actrIIb, ACVR2B, HTX4, wu:fj97d11, XAR1
list all ELISA KIts Gene Name GeneID UniProt
ACVR2B 93 Q13705
Rat ACVR2B ACVR2B 25366 P38445
ACVR2B 11481 P27040

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Horse (Equine) Activin A Receptor, Type IIB (ACVR2B) interaction partners

  1. ActRIIB mRNA but not protein was decreased in skeletal muscle of obese compared with lean animals.

Human Activin A Receptor, Type IIB (ACVR2B) interaction partners

  1. the A allele of genetic variant rs2276541 in ACVR2B is associated with lean muscle mass

  2. TGF-beta (show TGFB1 ELISA Kits) receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.(

  3. ActR-IIB is expressed in male germ cells and Sertoli cells.

  4. Activin A (show INHBA ELISA Kits) inhibited signaling by BMP-6 (show BMP6 ELISA Kits) and BMP-9 (show GDF2 ELISA Kits) by competing for type 2 receptors ACVR2A (show ACVR2A ELISA Kits) and ACVR2B.

  5. We found that the AAAAA, AGGAG, and AGGGA haplotypes in ACVR2B were associated with susceptibility to Premature Ovarian Failure when they also had at least one CATAG haplotype in ADAMTS19.

  6. miR (show MLXIP ELISA Kits)-21 interacts directly with the 3'-untranslated region of ACVR2B mRNA. Mechanical stretch suppressed ACVR2B protein levels in periodontal ligament stem cells. Gain- and loss of function of ACVR2B mediated the osteogenic differentiation of PDLSCs.

  7. Adenomyotic tissues express high levels of myostatin (show MSTN ELISA Kits), follistatin (show FST ELISA Kits), and activin (show Actbeta ELISA Kits) type II receptors.

  8. Activin type IIB receptors are clearly demonstrable throughout the adult human hypothalamus and basal forebrain.

  9. After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed lower levels of ActRIIb while postmenopausal women using HT showed a heightened response.

  10. The interaction between all five miRNAs and ACVR2B was verified by an in vitro assay.

Zebrafish Activin A Receptor, Type IIB (ACVR2B) interaction partners

  1. Roles in hindbrain and neural crest cell (NCC) patterning, in NCC derived pharyngeal arch cartilage and joint formation, and in tooth development.

Mouse (Murine) Activin A Receptor, Type IIB (ACVR2B) interaction partners

  1. Data, including data from studies using transgenic mice, suggest that osteoblasts deficient in Acvr2A (show ACVR2A ELISA Kits) exhibit un-characteristic features; osteoclasts deficient in Acvr2A (show ACVR2A ELISA Kits) or Acvr2B or both appear normal. Acvr2A (show ACVR2A ELISA Kits)-deficient mice exhibit significantly increased femoral trabecular bone volume at 6 weeks of age; Acvr2B-deficient mice exhibit no significant change in any bone parameter.

  2. Differential muscle hypertrophy is associated with satellite cell numbers and Akt (show AKT1 ELISA Kits) pathway activation following activin type IIB receptor inhibition in Mtm1 (show MTM1 ELISA Kits)

  3. ActRIIB inhibition enhanced energy expenditure only at ambient temperature or in the cold, where nonshivering thermogenesis is minimal, suggesting that brown fat activation plays a prominent role in the metabolic actions of ActRIIB inhibition.

  4. findings best fit a model in which BMP3 (show BMP3 ELISA Kits), produced by mature bone cells, acts to reduce BMP signaling through Acvr2b in skeletal progenitor cells, limiting their differentiation to mature osteoblasts

  5. Functional redundancy in osteoblast differentiation is observed between bone morphogenetic protein receptor BMPR-II (show BMPR2 ELISA Kits) and ActR-IIB.

  6. Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin (show MTM1 ELISA Kits)-deficient mice.

  7. Akt (show AKT1 ELISA Kits) isoforms are not essential for for the ability of ActRIIB inhibition to regulate muscle size and function .

  8. ActRIIB plays a role in the specification of left-sidedness in developing mice

  9. Activin (show Actbeta ELISA Kits) type IIB(ActRIIB) and its subfamily receptor, Activin (show Actbeta ELISA Kits) type IIA (ActRIIA (show ACVR2A ELISA Kits)), cooperatively mediate the Gdf11 (show GDF11 ELISA Kits) signal in patterning the axial vertebrae

  10. ActRIIB is expressed in the early development of thymocytes.

Activin A Receptor, Type IIB (ACVR2B) Antigen Profile

Antigen Summary

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

Alternative names and synonyms associated with Activin A Receptor, Type IIB (ACVR2B)

  • activin A receptor, type IIB (ACVR2B) Elisa Kit
  • activin A receptor, type IIB (acvr2b) Elisa Kit
  • activin A receptor, type IIB (Acvr2b) Elisa Kit
  • activin receptor IIb (acvr2b) Elisa Kit
  • activin receptor IIB (Acvr2b) Elisa Kit
  • ActR-IIB Elisa Kit
  • actr2b Elisa Kit
  • actrIIb Elisa Kit
  • ACVR2B Elisa Kit
  • HTX4 Elisa Kit
  • wu:fj97d11 Elisa Kit
  • XAR1 Elisa Kit

Protein level used designations for ACVR2B

activin A receptor, type IIB , activin receptor type IIB , activin receptor type-2B-like , activin type IIB receptor , activin receptor type-2B , ACTR-IIB , testicular activin receptor IIB , ActRIIB type II activin receptor B , Activine receptor 2b (transmembrane serine kinase) , activin receptor IIB

GENE ID SPECIES
443156 Ovis aries
460271 Pan troglodytes
100456564 Pongo abelii
448641 Xenopus (Silurana) tropicalis
696071 Macaca mulatta
100053588 Equus caballus
93 Homo sapiens
399277 Xenopus laevis
374213 Gallus gallus
485590 Canis lupus familiaris
448845 Sus scrofa
282131 Bos taurus
25366 Rattus norvegicus
30457 Danio rerio
11481 Mus musculus
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