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anti-Human CPLX3 Antibodies:
anti-Mouse (Murine) CPLX3 Antibodies:
anti-Rat (Rattus) CPLX3 Antibodies:
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Rat (Rattus) Monoclonal CPLX3 Primary Antibody for IHC, WB - ABIN1742266
Landgraf, Mühlhans, Dedek, Reim, Brandstätter, Ammermüller: The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina. in The European journal of neuroscience 2012
CPX (show CPOX Antibodies) acts sequentially on assembling SNAREpins, first facilitating zippering by nearly doubling the distance at which v- and t-SNAREs can engage and then clamping them into a half-zippered fusion-incompetent state.
This study links Cplx3 expression with synapse and circuit function in a specific retinal pathway and reveals a role for asynchronous release in circuit gain control.
The findings of this study reveal a suppressing action of Cplx3/4 on tonic neurotransmitter release, a facilitating action on evoked release, and a regulatory role of Cplx3/4 in the adaptation-dependent availability of synaptic vesicles at mouse photoreceptor ribbon synapses.
This study demonistrated that Cplx3-positive cells are generated during the 2-day peak of subplate neurogenesis (E11.5-E12.5). survive preferentially after the first postnatal week compared with other subplate neurons.
The lack of Cplx 3 and Cplx 4 (show CPLX4 Antibodies) differentially impacts the ON and OFF pathways in the retina is corroborated by localization studies of Cplx 3 and Cplx 4 (show CPLX4 Antibodies) in the retina.
The novel CPXs III and IV may contribute to the unique release efficacy of retinal sensory neurons.(cOMPLEXIN III, MOUSE)
Results show that complexin 3 and complexin 4 (show CPLX4 Antibodies) are essential regulators of transmitter release at retinal ribbon synapses.
Positively regulates a late step in synaptic vesicle exocytosis (By similarity).
, Complexin III
, CPX III
, complexin III
, lectin, mannose-binding, 1 like