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These results suggest direct roles for p38 MAPK (show MAPK14 Proteins) and SAC1 in transmitting growth signals to the secretory machinery.
Sac1 executes an essential household function in mammals that involves organization of both Golgi membranes and mitotic spindles
data suggest a model in which the 14-3-3 protein (show YWHAE Proteins) mediates SAC1 traffic from the ER through direct interaction with a sorting signal and COPII
membrane lipid phosphatase with activity toward phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate substrates
phosphatidylinositide phosphatase SAC1
, suppressor of actin mutations 1-like protein
, polyphosphatidylinositol phosphatase
, suppressor of actin 1