Browse our Solute Carrier Family 5 Member 3 Proteins (SLC5A3)

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Solute Carrier Family 5 Member 3 Proteins (SLC5A3)
On www.antibodies-online.com are 6 Solute Carrier Family 5 Member 3 (SLC5A3) Proteins from 2 different suppliers available. Additionally we are shipping Solute Carrier Family 5 Member 3 Antibodies (68) and many more products for this protein. A total of 77 Solute Carrier Family 5 Member 3 products are currently listed.
Synonyms:
AA623876, BF642829, Smit, SMIT1, SMIT2
list all proteins Gene Name GeneID UniProt
SLC5A3 53881 Q9JKZ2
SLC5A3 6526 P53794
Rat SLC5A3 SLC5A3 114507  

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Solute Carrier Family 5 Member 3 Proteins (SLC5A3) by Origin

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More Proteins for Solute Carrier Family 5 Member 3 Interaction Partners

Mouse (Murine) Solute Carrier Family 5 Member 3 (SLC5A3) interaction partners

  1. KCNQ1 (show KCNQ1 Proteins), KCNE2 (show KCNE2 Proteins), and SMIT1 form reciprocally regulating complexes that affect neuronal excitability.

  2. activation of NFAT5 (show NFAT5 Proteins) and its downstream SMIT induction is important in protecting neurons from ischemia-induced oxidative stress

  3. At low concentration, where SMIT1/2 activity gains importance, myo-inositol uptake is reduced by ammonia-induced intracellular acidification

  4. These findings add Mus (show TRPV6 Proteins) spicilegus endogenous retrovirus HEMV as a second member to the murine leukemia virus subgroup that uses mSMIT1 to gain entry into cells.

  5. brain SMIT1 levels were higher than SMIT2, however, regional differences were observed

  6. Sodium/MI cotransporter 1 (SMIT1, the major cotransporter of MI) knockout (SMIT1(-/-)) mice with markedly reduced tissue myoinositol (MI) levels were used to characterize the essential roles of MI and SMIT1 in osteogenesis.

  7. SLC5a3 is responsible for the Ins (show INS Proteins) concentration gradient in the murine fetal-placental unit

  8. used by Mus (show TRPV6 Proteins) cervicolor Murine Leukemia Virus for cell entry

  9. When Sertoli cells were cultured in a hypertonic medium, there was an increase in the expression of Isyna1 (show ISYNA1 Proteins) and Slc5a3

  10. SMIT-1 has a role in the development and function of the peripheral nerves

Human Solute Carrier Family 5 Member 3 (SLC5A3) interaction partners

  1. SMIT1 Modifies KCNQ (show KCNQ1 Proteins) Channel Function and Pharmacology by Physical Interaction with the Pore

  2. overexpression of the Na(+)/myo-inositol cotransporter (SMIT1) and myo-inositol supplementation enlarged intracellular PI(4,5)P2 pools, modulated several PI(4,5)P2-dependent ion channels including KCNQ2 (show KCNQ2 Proteins)/3 channels, and attenuated the action potential firing of superior cervical ganglion neurons

  3. Hypotonic stress causes a significant upregulation of SLC5A3 gene expression as detected by semiquantitative RT-PCR and Western blot analysis.

  4. A kinetic model has been generated for the transport mechanism of SMIT2 allowing insight into the transport of members of the LeuT structural family at the millisecond timescale.

  5. JAK2 (show JAK2 Proteins) contributes to the regulation of the myoinositol transporter SMIT.

  6. Tumor cells silence SLC5A8 and convert pyruvate into lactate as complementary mechanisms to avoid pyruvate-induced cell death.

  7. Expression and/or function of SMIT2 may be reduced in diabetes mellitus, insulin (show INS Proteins) resistance and polycystic ovary syndrome causing abnormal inositol meteabolism

Solute Carrier Family 5 Member 3 (SLC5A3) Protein Profile

Protein Summary

Functions as a retroviral receptor for M813 murine leukemia virus (MuLV) entry. Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.

Alternative names and synonyms associated with Solute Carrier Family 5 Member 3 (SLC5A3)

  • solute carrier family 5 (inositol transporters), member 3 (Slc5a3)
  • solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 (SLC5A3)
  • solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 (Slc5a3)
  • AA623876 protein
  • BF642829 protein
  • Smit protein
  • SMIT1 protein
  • SMIT2 protein

Protein level used designations for SLC5A3

Na(+)/myo-inositol cotransporter , sodium myo-inositol transporter 1 , sodium/myo-inositol cotransporter , sodium/myo-inositol transporter 1 , solute carrier family 5 member 3 , solute carrier family 5, member 3 , solute carrier family 5, member alpha 3 , BCW2 protein , human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter , sodium/myo-inositol cotransporter 1 , solute carrier family 5 (inositol transporter), member 3 , solute carrier family 5 (inositol transporters), member 3 , osmoregulatory Na+/myo-inositol cotransporter

GENE ID SPECIES
53881 Mus musculus
6526 Homo sapiens
114507 Rattus norvegicus
282362 Bos taurus
445542 Canis lupus familiaris
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