Your research always depends on good and reliable controls. Only in comparison to these will you be able to interpret your results correctly. This does not mean that things have to be very complicated. Very useful tools for the development of good controls are isotype controls. Isotype controls work as a substitute for antibodies and give information if unspecific binding of immunoglobulins occurs in your probe which has nothing to do with a specific antigen–antibody binding. Isotype controls have to be generated in the same species as the antibody. Of course they should also be applied in the same concentration as the antibody. On antibodies-online you find over 500 different isotype controls for various immunoglobulins generated in all common species. Compare the isotype controls of several suppliers on antibodies-online. Only antibodies-online provides you with suitable antibody and isotype controls in no time at all.