Mouse IgG1, kappa Isotype Control

Details for Product No. ABIN2656356, Supplier: Log in to see
Isotype
Host
Mouse
122
77
3
Clonality (Clone)
Monoclonal ()
Application
Isotype Control (IsoC), Western Blotting (WB)
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Clone MOPC-21
Isotype IgG1 kappa
Fragment Chain kappa
Characteristics The MOPC-21 immunoglobulin has unknown specificity. The isotype of this antibody is mouse IgG1, κ. This antibody was chosen as an isotype control after screening on a variety of resting, activated, live, and fixed mouse, rat and human tissues.
Purification The immunoglobulin was purified by affinity chromatography, and conjugated with Alexa Fluor® 700 under optimal conditions.
Alternative Name IgG1 kappa
Research Area Secondary Antibodies
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C
Background publications Correia, Fogli, Hudspeth, da Silva, Mavilio, Silva-Santos: "Differentiation of human peripheral blood Vδ1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells." in: Blood, Vol. 118, Issue 4, pp. 992-1001, 2011 (PubMed).

Smed-Sörensen, Moll, Cheng, Loré, Norlin, Perbeck, Moody, Spetz, Sandberg: "IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa." in: Blood, Vol. 111, Issue 10, pp. 5037-46, 2008 (PubMed).

Carlsten, Björkström, Norell, Bryceson, van Hall, Baumann, Hanson, Schedvins, Kiessling, Ljunggren, Malmberg: "DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells." in: Cancer research, Vol. 67, Issue 3, pp. 1317-25, 2007 (PubMed).

Matsuyama, Kawai, Izumi, Taubman: "Expression of major histocompatibility complex class II and CD80 by gingival epithelial cells induces activation of CD4+ T cells in response to bacterial challenge." in: Infection and immunity, Vol. 73, Issue 2, pp. 1044-51, 2005 (PubMed).