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anti-Mouse (Murine) CNTF Receptor alpha Antibodies:
anti-Rat (Rattus) CNTF Receptor alpha Antibodies:
anti-Human CNTF Receptor alpha Antibodies:
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Mouse (Murine) Polyclonal CNTF Receptor alpha Primary Antibody for ELISA, WB - ABIN188694
Yokota, Yoshikawa, Hirabayashi, Nakase, Uranishi, Nishimura, Sugie, Ishizaka, Sakaki: Expression of ciliary neurotrophic factor (CNTF), CNTF receptor alpha (CNTFR-alpha) following experimental intracerebral hemorrhage in rats. in Neuroscience letters 2005
Human Polyclonal CNTF Receptor alpha Primary Antibody for IF (p), IHC (p) - ABIN687637
Schwieger, Warnecke, Lenarz, Esser, Scheper: Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination. in PLoS ONE 2015
Human Monoclonal CNTF Receptor alpha Primary Antibody for WB - ABIN967627
Krüttgen, Grötzinger, Kurapkat, Weis, Simon, Thier, Schröder, Heinrich, Wollmer, Comeau: Human ciliary neurotrophic factor: a structure-function analysis. in The Biochemical journal 1995
CNTFR expression was downregulated by androgen in the inguinoscrotal fat pad suggesting that the genitofemoral nerve may be masculinised to control gubernacular migration in the inguinoscrotal phase of testicular descent by a negative regulating mechanism in mouse embryos .
The data of this study data suggest that CNTF (show CNTF Antibodies) receptors may promote adult motor neuron survival.
CNTF (show CNTF Antibodies)-Ralpha and CNTF (show CNTF Antibodies) are present in the pre-and post-synaptic sites of the neuromuscular junction.
Data show that CNTF receptor alpha subunit (show POLG Antibodies), CNTFRalpha, signaling in leptin (show LEP Antibodies)-responsive neurons is not required for endogenous maintenance of energy balance.
identification of neuropoietin as a new ligand with with important implications for murine nervous system development
CNTF (show CNTF Antibodies)-CNTFRalpha activates the JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) pathway leading to enhanced Cx43 (show GJA1 Antibodies) expression and intercellular coupling
It is suggested that the loss of CNTFRalpha from axons renders RGCs unresponsive to CNTF (show CNTF Antibodies), thereby contributing to regenerative failure and death, while its appearance on glia may promote glial scarring.
Co-administration of ciliary neurotrophic factor (show CNTF Antibodies) with its soluble receptor (show IFNAR1 Antibodies) protects against neuronal death and enhances neurite outgrowth.
CNTF (show CNTF Antibodies) receptor signaling, likely by the MNs (show GYPE Antibodies) themselves, can play an essential role in MN survival. This role is independent of any developmental contributions CNTF (show CNTF Antibodies) receptor signaling makes to MN survival or function.
The family-based study showed no association between the CNTFR rs7036351, NET rs3785143 polymorphisms, and attention-deficit hyperactivity disorder.
R28E mutation in CNTF (show CNTF Antibodies) abrogatesIL-6 receptor-dependent but retains CNTF (show CNTF Antibodies) receptor-dependent signaling via glycoprotein 130/ LIFR (show LIFR Antibodies).
gene expression and surface expression in NK92 cells of ciliary neurotrophic factor alpha (CNTFR-alpha) and glycoprotein (gp)130 in natural killer (NK) cells, in the context of malaria, were investigated.
Data indicate that CNTFRalpha plays a role in the formation or maintenance of tumor-initiating cells in gliomas, is a marker that correlates with histological grade, may underlie treatment resistance in some cases, and is a potential therapeutic target.
expression of neurotrophin (show BDNF Antibodies) receptors Pan (show SUPT6H Antibodies)-Trk (show NTRK1 Antibodies), p75 neurotrophin receptor (p75 (show NGFR Antibodies)(NTR (show NGFR Antibodies)) and ciliary neurotrophic factor receptor-alpha in ulveal melanoma does not show a role in growth.
Data show that variants in CNTFR were significantly associated with a lower age at onset of the eating disorders.
interactions of CNTFR with LIFR and gp130 in vitro
C174T polymorphism in exon 9 of CNTFR is significantly associated with fat-free (show VPS51 Antibodies) mass in men and women, with concomitant differences in muscular strength.
Structural and docking interaction studies showed that the R197L substitution destabilized the contact site between CLC (show CLC Antibodies) and CNTFRalpha.
In liver CNTFRalpha serves as a key modulator in regulating PI3K and AMP-activated protein kinase dynamically under CNTF stimulation, resulting in the increase of glucose uptake and translocation of glucose transporter 4.
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
, ciliary neurotrophic factor receptor
, ciliary neurotrophic factor receptor subunit alpha
, ciliary neurotrophic factor receptor subunit alpha preproprotein
, ciliary neurotrophic factor receptor subunit alpha-like
, CNTF receptor subunit alpha
, ciliary neurotrophic factor receptor alpha
, GPA receptor subunit alpha
, growth promoting activity (GPA) receptor alpha; GPARalpha
, growth-promoting activity receptor subunit alpha