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Browse our CSF2RB Proteins (CSF2RB)

Full name:
Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) Proteins (CSF2RB)
On www.antibodies-online.com are 12 Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) Proteins from 6 different suppliers available. Additionally we are shipping CSF2RB Antibodies (95) and CSF2RB Kits (14) and many more products for this protein. A total of 130 CSF2RB products are currently listed.
Synonyms:
AI848964, AIC2B, Bc, CD131, CDw131, CSF2RB, Csf2rb1, Csfgmrb, il-3rbc, Il3r, Il3rb, Il3rb1, Il5rb, SMDP5
list all proteins Gene Name GeneID UniProt
CSF2RB 171081  
CSF2RB 1439 P32927
CSF2RB 12983 P26955

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CSF2RB Proteins (CSF2RB) by Origin

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Top referenced CSF2RB Proteins

  1. Human CSF2RB Protein expressed in Human Cells - ABIN2002989 : Carr, Gustin, Church, Murphy, Ford, Mann, Woltring, Walker, Ollis, Young: Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration. in Cell 2001 (PubMed)
    Show all 3 references for ABIN2002989

  2. Rat (Rattus) CSF2RB Protein expressed in Human Cells - ABIN2009482 : Mulhern, Lopez, DAndrea, Gaunt, Vandeleur, Vadas, Booker, Bagley: The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5. in Journal of molecular biology 2000 (PubMed)
    Show all 3 references for ABIN2009482

More Proteins for CSF2RB Interaction Partners

Human Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) interaction partners

  1. VitD-mediated stimulation of GC anti-inflammatory affects human monocytes in a process involving GM-CSF and MED14

  2. These data suggest that expression of GM-CSF (show CSF2 Proteins) and its receptor subunits by colon tumors may be a useful marker for prognosis

  3. This study reveals a novel functional role of clathrin-coated structure in GMR (show CSF2RA Proteins) signaling and the oncogenesis of JAK2V617F.

  4. JAK (show JAK3 Proteins) kinase binding to betac requires the presence of three critical betac lysine residues, and this binding event is essential for receptor ubiquitination, endocytosis, and signaling.

  5. Granulocyte/macrophage colony-stimulating factor (show CSF2 Proteins) causes a paradoxical increase in the BH3-only (show BBC3 Proteins) pro-apoptotic protein Bim (show BCL2L11 Proteins) in human neutrophils

  6. The results of the study support CSF2RB as a risk factor common to both schizophrenia and major depression in the Chinese Han population.

  7. Hereditary pulmonary alveolar proteinosis caused by recessive CSF2RB mutations [case report]

  8. The beta1 integrin-interacting domain in the extracellular domain of IL-3Rbeta was identified. A fragment of a protein corresponding to domain 4 of IL-3Rbeta prevented IL-3 (show Il3 Proteins)-mediated arterial morphogenesis and endothelial cell migration.

  9. the domain 1 D-E loop disulfide of hbetac and beta(IL-3 (show Il3 Proteins)) have roles in maintaining the precise positions of ligand-binding residues necessary for normal high affinity binding and signaling

  10. Data show that Deletion of the Ig-like domain of GM-CSFRalpha (show CSF2RA Proteins) abolished direct GM-CSF (show CSF2 Proteins) binding and decreased growth signalling in the presence of hbetac.

Mouse (Murine) Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) interaction partners

  1. blockage of betaCR abrogated the EPO (show EPO Proteins)-conferred anti-inflammatory action on oxLDL-induced production of macrophage inflammatory protein-2 (show CXCL2 Proteins)

  2. Deletion of the Csf2rb gene slows the progression of chronic myelomonocytic leukemia in mice.

  3. Increased levels of Csf2rb on hematopoietic stem cells lead to expansion of these populations in ApoE (show APOE Proteins)(-/-) BM-transplanted Ldlr (show LDLR Proteins)(-/-) mice, contributing to monocytosis and increased lesional macrophage content.

  4. Erythropoietin (show EPO Proteins) attenuates the impaired systolic contractility associated with sepsis by activation of the beta-common receptor.

  5. Findings indicate that SLP-76 (show LCP2 Proteins) is an essential signaling component for basophil activation downstream of both FcepsilonRI (show FCER1A Proteins) and the IL-3 (show Il3 Proteins) receptor.

  6. Csf-2 (show CSF2 Proteins) receptor acts in the steady state to promote the survival & homeostasis of nonlymphoid tissue-resident CD103 (show ITGAE Proteins)(+) & CD11b (show ITGAM Proteins)(+) DCs. It is dispensable for the differentiation & innate function of inflammatory DCs during acute injuries.

  7. GM-CSF can regulate beta-catenin stability, most likely via GSK3b.

  8. Suggest that beta common receptor may play an integrative role in the erythropoietin (show EPO Proteins) signaling-mediated activation of eNOS (show NOS3 Proteins) in endothelial cells.

  9. NF-kappaB (show NFKB1 Proteins) activation by beta(c) is dependent on TNFR (show TNFRSF1A Proteins)-associated factor (TRAF)6 (show TRAF6 Proteins); association of TRAF6 (show TRAF6 Proteins) with beta(c) requires a consensus-binding motif found in other molecules known to interact with TRAF6 (show TRAF6 Proteins).

  10. Interleukin-3 (show Il3 Proteins) binding to the murine betaIL-3 receptor involves functional epitopes formed by domains 1 and 4 of different protein chains

Cow (Bovine) Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) interaction partners

  1. Suggest that beta common receptor may play an integrative role in the erythropoietin (show EPO Proteins) signaling-mediated activation of eNOS (show NOS3 Proteins) in endothelial cells.

CSF2RB Protein Profile

Protein Summary

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).

Alternative names and synonyms associated with CSF2RB

  • colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (CSF2RB)
  • colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb)
  • colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (csf2rb)
  • AI848964 protein
  • AIC2B protein
  • Bc protein
  • CD131 protein
  • CDw131 protein
  • CSF2RB protein
  • Csf2rb1 protein
  • Csfgmrb protein
  • il-3rbc protein
  • Il3r protein
  • Il3rb protein
  • Il3rb1 protein
  • Il5rb protein
  • SMDP5 protein

Protein level used designations for CSF2RB

cytokine receptor common subunit beta , interleukin 3 common beta chain , colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage) , colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) , interleukin 3 receptor beta common , cytokine receptor common subunit beta-like , GM-CSF/IL-3/IL-5 receptor common beta subunit , GM-CSF/IL-3/IL-5 receptor common beta-chain , colony-stimulating factor-2 receptor, beta, low-affinity , interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity) , CD131 antigen , beta c , common beta chain , interleukin-5 receptor beta chain

GENE ID SPECIES
100054613 Equus caballus
171081 Rattus norvegicus
458802 Pan troglodytes
481276 Canis lupus familiaris
495479 Xenopus laevis
697508 Macaca mulatta
771315 Gallus gallus
100135062 Danio rerio
100393477 Callithrix jacchus
100457063 Pongo abelii
100477536 Ailuropoda melanoleuca
100594820 Nomascus leucogenys
1439 Homo sapiens
12983 Mus musculus
100153254 Sus scrofa
528530 Bos taurus
100192395 Cavia porcellus
100349996 Oryctolagus cuniculus
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