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anti-Chicken GNAQ antibody for Western Blotting

Recommended GNAQ Antibody (supplied by: Log in to see )

Antigen
Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antibodies
  • 1110005L02Rik
  • 6230401I02Rik
  • AA408290
  • AW060788
  • CMC1
  • Dsk1
  • Dsk10
  • G-ALPHA-q
  • g-alpha-q
  • Galphaq
  • gaq
  • GAQ
  • Gnaq
  • gnaqb
  • Gq
  • GqI
  • si:ch73-270f14.2
  • SWS
Epitope
AA 22-31
21
16
13
13
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
71
28
25
6
3
2
1
Host
Mouse
51
13
8
Clonality
Monoclonal
Conjugate
This GNAQ antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
58
35
14
11
3
1
Supplier
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Catalog No. ABIN968914
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.12303223 ABIN968915 IF WB Mouse IgG1 AA 22-31 Log in to see 10-GAQ 3

Top referenced anti-GNAQ antibody for Western Blotting

Similar anti-GNAQ Antibodies

Application / Reactivity Human Dog (Canine) Mouse (Murine) Rat (Rattus) Chicken
Western Blotting (WB) 59 Antibodies 7 Antibodies 18 Antibodies 15 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies 6 Antibodies 6 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 3 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies

General

Antigen Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) Antibodies
Epitope AA 22-31
(21), (16), (13), (13), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(71), (28), (25), (6), (3), (2), (1)
Host Mouse
(51), (13), (8)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GNAQ antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Western Blotting (WB)
(58), (35), (14), (11), (3), (1)
Pubmed 3 references available
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Product Details anti-GNAQ Antibody

Target Details GNAQ Application Details Handling References for anti-GNAQ Antibody (ABIN968914) Images
Cross-Reactivity Mouse (Murine), Rat (Rattus), Chicken, Dog (Canine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Galphaq aa. 22-31
Clone 10-GAQ
Isotype IgG1

Target Details GNAQ

Product Details anti-GNAQ Antibody Application Details Handling References for anti-GNAQ Antibody (ABIN968914) Images back to top
Antigen
Alternative Name Galpha q (GNAQ Antibody Abstract)
Background The GTP binding regulatory proteins (G proteins) consist of three subunits: alpha, beta, and gamma. These heterotrimeric proteins function at membranes to relay signals from cell surface receptors to intracellular effectors. The alpha subunit is unique for each G protein and contains the site of GTP binding and hydrolysis, as well sites for receptor and effector interactions. The betagamma subunit complex interacts directly with receptors and the alpha subunit. The Galpha family includes four families: the Galphas family including Galphas , Galphao1f, and Galphat, the Galphai family including Galphai, Galphao, and Galphaz, the Galphaq/Galpha11 family and the Galpha12/13 family. The Galphaq protein is 88% homologus with Galpha11 and both are widely expressed. These G proteins activate phospholipase C proteins, which induce calcium signaling events. G protein coupled receptors (GPCRs) involved in regulating Wnt signaling activate Galphaq, phospholipase Cbeta, and induce calcium-dependent activation of calpain. These events promote beta-catenin nuclear export and proteolysis. Galphaq has also been implicated in metabotropic glutamate receptor signaling. Thus, Galphaq isoforms activate phospholipase C proteins in various G-protein coupled receptor pathways.
Molecular Weight 42 kDa
Pathways JAK-STAT Signaling

Application Details

Product Details anti-GNAQ Antibody Target Details GNAQ Handling References for anti-GNAQ Antibody (ABIN968914) Images back to top
Comment

Related Products: ABIN968537, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-GNAQ Antibody Target Details GNAQ Application Details References for anti-GNAQ Antibody (ABIN968914) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.

References for anti-GNAQ Antibody (ABIN968914)

Product Details anti-GNAQ Antibody Target Details GNAQ Application Details Handling Images back to top
Product cited in:

Dutt, Kjoller, Giel, Hall, Toksoz: "Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly." in: FEBS letters, Vol. 531, Issue 3, pp. 565-9, 2002

Li, Iyengar: "Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 13254-9, 2002

Strathmann, Simon: "G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 23, pp. 9113-7, 1991

Images

Product Details anti-GNAQ Antibody Target Details GNAQ Application Details Handling References for anti-GNAQ Antibody (ABIN968914) back to top
Supplier Images
Western Blotting (WB) image for anti-GNAQ antibody (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide) (AA 22-31) (ABIN968914) Western blot analysis of Galphaq on a Jurkat cell lysate (Human T-cell leukemia, ATCC...
Immunofluorescence (IF) image for anti-GNAQ antibody (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide) (AA 22-31) (ABIN968914) Immunofluorescence staining of PC12 cells (Rat neuroblastoma, ATCC CRL-1721) treated ...