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anti-Mouse (Murine) IFNA2 Antibodies:
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Human Monoclonal IFNA2 Primary Antibody for Func, EIA - ABIN1107639
Kontsek, Borecky, Kontsekova, Macikova, Kolcunova, Novak, Krchnak: Mapping of two immunodominant structures on human interferon alpha 2c and their role in binding to cells. in Molecular immunology 1992
Show all 2 references for ABIN1107639
Human Monoclonal IFNA2 Primary Antibody for EIA - ABIN1107637
Adolf: Antigenic structure of human interferon omega 1 (interferon alpha II1): comparison with other human interferons. in The Journal of general virology 1987
Show all 2 references for ABIN1107637
IFNa (show IFNA Antibodies) and IFNc show similar antiviral activities and ability to induce antiviral genes in lymphoid tissues.
Data indicate that the combination of AAV2.IL-4 (show IL4 Antibodies) and AAV2.IFN-alpha (show IFNA Antibodies) was not significantly different as compared to AAV2.IL-4 (show IL4 Antibodies) alone.
Infecting virus and the target cell type dictate the extent and signature of inducible IFN-alpha2 gene expression.
Mutation of the IFNAR-1 (show IFNAR1 Antibodies) receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists.
produced in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus in lymph nodes cells expressing the myeloid markers CD14 (show CD14 Antibodies), CD11b (show ITGAM Antibodies), and CD172a (show SIRPA Antibodies)
Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 (show STAT1 Antibodies) and, to a lesser extent, STAT2 (show STAT2 Antibodies).
Data suggest IFNA2 binding to extracellular domain of IFN receptors IFNAR1 (show IFNAR1 Antibodies) or IFNAR2 (show IFNAR2 Antibodies) promotes proximity between intracellular domains; signaling depends on duration of activation and affinity of binding rather than specific conformational changes.
Report biased expression of human interferon alpha-2b and Escherichia coli methionine amino peptidase genes under control of single promoter in E. coli.
interferon alpha-2b gene mutations were identified among brain tumor patients; highest percentage of frameshift mutations was identified; patients were found to be under environmental stress from contaminated drinking water and from local gamma radiations
PPARalpha (show PPARA Antibodies) activation by an agonist WY-14643 could potentiate IFN-alpha (show IFNA Antibodies) responses, reverse IFN-alpha (show IFNA Antibodies) refractoriness, and enhance viral eradication in hepatocytes.
The chronic use of low dose of radiations by occupational workers has a significant correlation with mutational effects on interferon alpha 2b gene, further evident by depressed interferon alpha (show IFNA Antibodies) levels in serum.
IFN-beta (show IFNB1 Antibodies) was significantly more effective than IFNA2 in protecting human head and neck squamous cell carcinoma lines from oncolysis by vesicular stomatitis.
The structure, mechanism of action and biological activities of IFNalpha2. [Review]
Therefore, this study associated, for the first time, in a large panel of pancreatic cancer cell lines the effects of IFN-alpha (show IFNA Antibodies)/-beta with the expression of type-I IFN receptors.
these findings establish critical and essential roles for SKAR (show POLDIP3 Antibodies) in the regulation of mRNA translation of IFN-sensitive genes and induction of IFN-alpha (show IFNA Antibodies) biological responses.
Our data demonstrate disturbances in DC number and function expressed most significantly in T1D relatives and point to a potential role of TLR9 (show TLR9 Antibodies)-induced IFN-alpha (show IFNA Antibodies) production in T1D development.
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold.
, interferon alpha 2
, interferon alpha family, gene 2
, interferon alpha A
, IFN-alpha 2
, interferon-alpha 2
, alpha-2a interferon
, interferon alpha 2a
, interferon alpha 2b
, leIF A