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anti-Mouse (Murine) IFNAR1 antibody for Immunohistochemistry

Recommended IFNAR1 Antibody (supplied by: Log in to see )

Antigen
Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies
  • AVP
  • CD118
  • Ifar
  • IFN-alpha-REC
  • IFN-R-1
  • IFNAR
  • Ifnar
  • ifnar1
  • IFNAR1
  • IFNBR
  • IFRC
  • Ifrc
  • Infar
Reactivity
Mouse (Murine)
136
37
20
2
2
2
1
1
Host
Mouse
108
32
22
Clonality
Monoclonal
Conjugate
This IFNAR1 antibody is conjugated to Biotin
12
11
10
8
6
4
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
93
68
37
35
22
10
7
5
4
2
1
1
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Catalog No. ABIN2661194
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011425724 ABIN2665931 FACS IP IHC Mouse IgG1 kappa Log in to see MAR1-5A3 12
0.0011425724 ABIN2661195 FACS IHC Biotin Mouse IgG1 kappa Log in to see MAR1-5A3 12
0.0011425724 ABIN1582221 IHC ELISA WB Rabbit pSer535, pSer539 Log in to see Polyclonal
0.0011425724 ABIN2665930 FACS IP IHC Mouse IgG1 kappa Log in to see MAR1-5A3 12

Top referenced anti-IFNAR1 antibody for Immunohistochemistry

Similar anti-IFNAR1 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 6 Antibodies
ELISA (Detection) 4 Antibodies
Flow Cytometry (FACS) 10 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies
Reactivity Mouse (Murine)
(136), (37), (20), (2), (2), (2), (1), (1)
Host Mouse
(108), (32), (22)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IFNAR1 antibody is conjugated to Biotin
(12), (11), (10), (8), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Immunohistochemistry (IHC)
(93), (68), (37), (35), (22), (10), (7), (5), (4), (2), (1), (1)
Pubmed 12 references available
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Product Details anti-IFNAR1 Antibody

Target Details IFNAR1 Application Details Handling References for anti-IFNAR1 Antibody (ABIN2661194) Images
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone MAR1-5A3
Isotype IgG1 kappa

Target Details IFNAR1

Product Details anti-IFNAR1 Antibody Application Details Handling References for anti-IFNAR1 Antibody (ABIN2661194) Images back to top
Antigen
Alternative Name IFNAR-1 (IFNAR1 Antibody Abstract)
Background IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Handling References for anti-IFNAR1 Antibody (ABIN2661194) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details References for anti-IFNAR1 Antibody (ABIN2661194) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IFNAR1 Antibody (ABIN2661194)

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling Images back to top
Background publications

Jones, Stumhofer, Foster, Twohig, Hertzog, Topley, Williams, Hunter, Jenkins, Wang, Jones: "Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 1, pp. 409-19, 2011

Kelly-Scumpia, Scumpia, Delano, Weinstein, Cuenca, Wynn, Moldawer: "Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10." in: The Journal of experimental medicine, Vol. 207, Issue 2, pp. 319-26, 2010

Swanson, Wilson, Strauch, Colonna, Pelanda, Torres: "Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response." in: The Journal of experimental medicine, Vol. 207, Issue 7, pp. 1485-500, 2010

Habjan, Pichlmair, Elliott, Overby, Glatter, Gstaiger, Superti-Furga, Unger, Weber: "NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase." in: Journal of virology, Vol. 83, Issue 9, pp. 4365-75, 2009

Miller, Ma, Bian, Sheehan, Zachary, Weis, Schreiber, Weis: "A critical role for type I IFN in arthritis development following Borrelia burgdorferi infection of mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 12, pp. 8492-503, 2008

Swann, Hayakawa, Zerafa, Sheehan, Scott, Schreiber, Hertzog, Smyth: "Type I IFN contributes to NK cell homeostasis, activation, and antitumor function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 12, pp. 7540-9, 2007

Sheehan, Lai, Dunn, Bruce, Diamond, Heutel, Dungo-Arthur, Carrero, White, Hertzog, Schreiber: "Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 26, Issue 11, pp. 804-19, 2006

Dunn, Bruce, Sheehan, Shankaran, Uppaluri, Bui, Diamond, Koebel, Arthur, White, Schreiber: "A critical function for type I interferons in cancer immunoediting." in: Nature immunology, Vol. 6, Issue 7, pp. 722-9, 2005

Hemmi, Böhni, Stark, Di Marco, Aguet: "A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells." in: Cell, Vol. 76, Issue 5, pp. 803-10, 1994

Novick, Cohen, Rubinstein: "The human interferon alpha/beta receptor: characterization and molecular cloning." in: Cell, Vol. 77, Issue 3, pp. 391-400, 1994

Orchansky, Novick, Fischer, Rubinstein: "Type I and Type II interferon receptors." in: Journal of interferon research, Vol. 4, Issue 2, pp. 275-82, 1984

Branca, Baglioni: "Evidence that types I and II interferons have different receptors." in: Nature, Vol. 294, Issue 5843, pp. 768-70, 1982

Images

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling References for anti-IFNAR1 Antibody (ABIN2661194) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IFNAR1 antibody (Interferon (Alpha, beta and Omega) Receptor 1)  (Biotin) (ABIN2661194) anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) antibody (Biotin)