anti-Mouse (Murine) IFNAR1 antibody for Western Blotting

Recommended IFNAR1 Antibody (supplied by: Log in to see )

Antigen
Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies
  • ifnar1
  • IFNAR1
  • CD118
  • Ifar
  • Ifnar
  • Ifrc
  • Infar
  • AVP
  • IFN-alpha-REC
  • IFNAR
  • IFNBR
  • IFRC
  • IFN-R-1
  • interferon (alpha, beta and omega) receptor 1
  • interferon-alpha/beta receptor alpha chain-like
  • interferon receptor 1
  • interferon (alpha and beta) receptor 1
  • type I interferon receptor 1e
  • IFNAR1
  • ifnar1
  • LOC100230358
  • Ifnar1
  • IFNAR1E
Epitope
AA 1-429
27
26
17
17
15
15
11
10
8
6
6
6
5
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
176
45
27
4
3
2
1
1
Host
Rabbit
119
58
28
Clonality
Polyclonal
Conjugate
This IFNAR1 antibody is un-conjugated
14
11
11
9
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
1
Application
ELISA, Western Blotting (WB)
115
72
66
39
26
16
9
7
6
5
5
4
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2000997
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN1582221 IHC ELISA WB Rabbit pSer535, pSer539 Log in to see Polyclonal
1 ABIN5518761 WB Rabbit IgG AA 263-306, Middle Region Log in to see Polyclonal
1 ABIN802353 IF (p) IHC (p) WB Rabbit IgG AA 510-550, pSer535, pSer538 Log in to see Polyclonal
1 ABIN5551580 IHC (fro) WB Rabbit IgG pSer535, pSer539 Log in to see Polyclonal
1 ABIN2000999 ELISA WB Rabbit IgG AA 1-429 Log in to see Polyclonal 2
1 ABIN802362 IHC (p) WB HRP Rabbit IgG AA 510-550, pSer535, pSer538 Log in to see Polyclonal
1 ABIN802355 IHC (p) WB Biotin Rabbit IgG AA 510-550, pSer535, pSer538 Log in to see Polyclonal
1 ABIN228236 IHC WB Rabbit pSer535, pSer539 Log in to see Polyclonal
1 ABIN1820786 WB Rabbit IgG pSer535, pSer539 Log in to see Polyclonal
1 ABIN4904010 FACS IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2622359 ELISA WB FITC Rabbit IgG AA 104-341 Log in to see Polyclonal
1 ABIN2622352 ELISA WB Biotin Rabbit IgG AA 104-341 Log in to see Polyclonal
1 ABIN4904011 FACS IHC IP WB Rabbit IgG Log in to see
1 ABIN2622351 ELISA WB Rabbit IgG AA 104-341 Log in to see Polyclonal
1 ABIN2935141 ELISA IF/ICC IHC WB Rabbit AA 104-341 Log in to see Polyclonal

General

Antigen Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) Antibodies
Epitope AA 1-429
(27), (26), (17), (17), (15), (15), (11), (10), (8), (6), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(176), (45), (27), (4), (3), (2), (1), (1)
Host Rabbit
(119), (58), (28)
Clonality
Polyclonal
Conjugate This IFNAR1 antibody is un-conjugated
(14), (11), (11), (9), (6), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application ELISA, Western Blotting (WB)
(115), (72), (66), (39), (26), (16), (9), (7), (6), (5), (5), (4), (2), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-IFNAR1 Antibody

Target Details IFNAR1 Application Details Handling References for anti-IFNAR1 antibody (ABIN2000997) Images
Specificity Mouse IFNAR-1 / CRF2-1
Characteristics Produced in rabbits immunized with purified, recombinant Mouse IFNAR-1 / CRF2-1 (rM IFNAR-1, ABIN2007843 NP_034638.2, Met 1-Thr 429,. Total IgG was purified by Protein A affinity chromatography .
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Mouse IFNAR-1 protein (ABIN2007843)
Isotype IgG

Target Details IFNAR1

Product Details anti-IFNAR1 Antibody Application Details Handling References for anti-IFNAR1 antibody (ABIN2000997) Images back to top
Antigen
Alternative Name IFNAR1 (IFNAR1 Antibody Abstract)
Background Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors.
NCBI Accession NP_034638.2
Research Area Chromatin and Nuclear Signaling, Innate Immunity, Cytokines
Pathways JAK-STAT Signaling, Hepatitis C

Application Details

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Handling References for anti-IFNAR1 antibody (ABIN2000997) Images back to top
Application Notes WB: 10-20 μg/mL
ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Mouse IFNAR-1. The detection limit for Mouse IFNAR-1 is approximately 0.00975 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details References for anti-IFNAR1 antibody (ABIN2000997) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

References for anti-IFNAR1 antibody (ABIN2000997)

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling Images back to top
Background publications

Richter, Duménil, Uzé, Fellous, Pellegrini: "Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1." in: The Journal of biological chemistry, Vol. 273, Issue 38, pp. 24723-9, 1998

Abramovich, Yakobson, Chebath, Revel: "A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor." in: The EMBO journal, Vol. 16, Issue 2, pp. 260-6, 1997

Images

Product Details anti-IFNAR1 Antibody Target Details IFNAR1 Application Details Handling References for anti-IFNAR1 antibody (ABIN2000997) back to top
Supplier Images
Western Blotting (WB) image for anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) (AA 1-429) antibody (ABIN2000997) anti-Interferon (Alpha, beta and Omega) Receptor 1 (IFNAR1) (AA 1-429) antibody