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|Application / Reactivity||Cynomolgus|
|Antigen||Interleukin 13 (IL13) Antibodies|
|Epitope||AA 21-132 Alternatives|
|Conjugate||This IL-13 antibody is un-conjugated Alternatives|
|Supplier||Log in to see|
Product Details anti-IL-13 AntibodyTarget Details IL-13 Application Details Handling Images
|Characteristics||Produced in rabbits immunized with purified, recombinant Cynomolgus IL-13 (rC IL-13, ABIN2003836 ABG75889.1, Ser 21-Asn 132,. IL-13 specific IgG was purified by Cynomolgus IL-13 affinity chromatography.|
|Purification||purified by affinity chromatography|
|Sterility||0.2 μm filtered|
|Immunogen||Recombinant Cynomolgus IL-13 protein (ABIN2003836)|
Target Details IL-13Product Details anti-IL-13 Antibody Application Details Handling Images back to top
|Alternative Name||IL13 (IL13 Antibody Abstract)|
|Background||Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.|
|Research Area||Cancer, Cytokines, Innate Immunity|
|Pathways||JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport|
Application DetailsProduct Details anti-IL-13 Antibody Target Details IL-13 Handling Images back to top
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Cynomolgus IL13. The detection limit for Cynomolgus IL13 is approximately 0.039 ng/well.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL-13 Antibody Target Details IL-13 Application Details Images back to top
|Buffer||0.2 μm filtered solution in PBS with 5 % trehalose|
|Handling Advice||Avoid repeated freeze-thaw cycles.|
|Storage||4 °C,-20 °C,-80 °C|
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
|Expiry Date||12 months|