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anti-Mouse (Murine) IL-13 antibody for Neutralization

Recommended IL-13 Antibody (supplied by: Log in to see )

Antigen
Interleukin 13 (IL13) Antibodies
  • Il-13
  • IL-13
  • IL13
  • L13
  • P600
Reactivity
Mouse (Murine)
243
86
50
9
8
6
3
1
1
1
Host
Rat
159
113
88
7
Clonality
Monoclonal
Conjugate
This IL-13 antibody is un-conjugated
42
18
13
7
6
6
6
5
5
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Neutralization (Neut)
211
211
83
50
38
35
17
12
12
12
11
10
10
7
6
5
5
4
3
3
2
1
1
Supplier
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Catalog No. ABIN282535
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087378395 ABIN223546 Neut ELISA WB Rabbit IgG Log in to see Polyclonal 1
0.00087378395 ABIN465389 Neut ELISA WB Rabbit Log in to see Polyclonal
0.00087378395 ABIN242219 Neut ELISA WB Rabbit Log in to see Polyclonal
0.00087378395 ABIN1983763 Neut WB Rat IgG2 AA 26-131 Log in to see RM0259-15B9
0.00087378395 ABIN2290618 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
0.00087378395 ABIN1827280 Neut Rat IgG1, kappa Log in to see 1316H

Top referenced anti-IL-13 antibody for Neutralization

Similar anti-IL-13 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Antibody (Inhibition) 2 Antibodies
ELISA 41 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
ELISpot 2 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 1 Antibodies
ELISpot (Detection) (ELISPOT (Detection)) 1 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 13 Antibodies
Functional Studies (Func) 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Intracellular Staining (ICS) 7 Antibodies
Neutralization (Neut) 7 Antibodies
Western Blotting (WB) 43 Antibodies

General

Antigen Interleukin 13 (IL13) Antibodies
Reactivity Mouse (Murine)
(243), (86), (50), (9), (8), (6), (3), (1), (1), (1)
Host Rat
(159), (113), (88), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL-13 antibody is un-conjugated
(42), (18), (13), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Neutralization (Neut)
(211), (211), (83), (50), (38), (35), (17), (12), (12), (12), (11), (10), (10), (7), (6), (5), (5), (4), (3), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL-13 Antibody

Target Details IL-13 Application Details Handling References for anti-IL-13 Antibody (ABIN282535) Images
Specificity The antibody reacts with mouse IL-13. The 1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4, this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
Characteristics The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4, this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
Synonyms: Synonyms: Interleukin-13
Purification Affinity Purified
Endotoxin Level <0.001 ng endotoxin/μg
Grade Functional Grade
Clone 1316H
Isotype IgG1 kappa

Target Details IL-13

Product Details anti-IL-13 Antibody Application Details Handling References for anti-IL-13 Antibody (ABIN282535) Images back to top
Antigen
Alternative Name IL-13 (IL13 Antibody Abstract)
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL-13 Antibody Target Details IL-13 Handling References for anti-IL-13 Antibody (ABIN282535) Images back to top
Application Notes Applications reported: The eBio1316H antibody has been reported useful for neutralization, ELISA detection, and ELISPOT detection.

Applications tested: The Functional Grade purified format of the eBio1316H antibody has been tested by LAL assay to verify low endotoxin level and by bioassay to quantitate neutralization of IL-13 biological activity. For in vitro neutralization, the Functional Grade purified eBio1316H antibody at 0.04 μg/mL has been found to neutralize by 50 % the biological effect of 7.5 ng/mL mouse IL-13 in an assay of TF-1 cell proliferation. Detailed information and protocols about cytokine bioassays and in vitro cytokine neutralization using antibodies can be found in the BestProtocols® section.
Restrictions For Research Use only

Handling

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details References for anti-IL-13 Antibody (ABIN282535) Images back to top
Concentration 1 mg/mL
Buffer aqueous buffer, no sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Use in sterile environment.
Storage 4 °C

References for anti-IL-13 Antibody (ABIN282535)

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details Handling Images back to top
Product cited in:

Park, Chen, Esmaeil, Lucas, Marsh, Reibman, Grunig: "Interleukin 13- and interleukin 17A-induced pulmonary hypertension phenotype due to inhalation of antigen and fine particles from air pollution." in: Pulmonary circulation, Vol. 4, Issue 4, pp. 654-68, 2015

Images

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details Handling References for anti-IL-13 Antibody (ABIN282535) back to top
Supplier Images
 image for anti-IL-13 antibody (Interleukin 13) (ABIN282535) Mouse IL-13 ELISPOT: Splenocytes were activated with immobilized anti-CD3 and anti-CD...
 image for anti-IL-13 antibody (Interleukin 13) (ABIN282535) anti-Interleukin 13 (IL13) antibody (Image 2)