anti-Pig (Porcine) IL-13 antibody for Enzyme Immunoassay

Recommended IL-13 Antibody (supplied by: Log in to see )

Antigen
Interleukin 13 (IL13) Antibodies
  • IL13
  • IL-13
  • P600
  • Il-13
  • L13
  • interleukin 13
  • interleukin-13
  • IL13
  • Il13
  • IL-13
Reactivity
Pig (Porcine)
271
82
54
9
9
5
3
2
1
1
1
Host
Rabbit
161
150
70
5
4
Clonality
Polyclonal
Conjugate
This IL-13 antibody is un-conjugated
39
14
14
10
10
9
9
7
7
7
6
6
4
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
210
204
125
55
48
28
23
13
12
11
11
10
10
7
7
4
4
3
3
2
2
1
1
1
1
1
1
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Catalog No. ABIN401064
$ 419.10
Plus shipping costs $45.00

General

Antigen Interleukin 13 (IL13) Antibodies
Reactivity Pig (Porcine)
(271), (82), (54), (9), (9), (5), (3), (2), (1), (1), (1)
Host Rabbit
(161), (150), (70), (5), (4)
Clonality
Polyclonal
Conjugate This IL-13 antibody is un-conjugated
(39), (14), (14), (10), (10), (9), (9), (7), (7), (7), (6), (6), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(210), (204), (125), (55), (48), (28), (23), (13), (12), (11), (11), (10), (10), (7), (7), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL-13 Antibody

Target Details IL-13 Application Details Handling References for anti-IL-13 antibody (ABIN401064) Images
Specificity This antibody reacts to Interleukin-13.
Cross-Reactivity (Details) Species reactivity (expected):Sheep, Dolphin, Beluga, Bovine, Human, Certain monkey, Dusky titi, Macaque, Baboon, Mangabey, Canine, Llama, Camel, Galago, Horse, Rat, Mouse, Gerbil.
Species reactivity (tested):Porcine.
Purification Affinity chromatography on Protein A
Immunogen Full length recombinant protein raised in yeast, corresponding to mature swine IL-13 protein
Isotype IgG

Target Details IL-13

Product Details anti-IL-13 Antibody Application Details Handling References for anti-IL-13 antibody (ABIN401064) Images back to top
Antigen
Alternative Name Interleukin-13 / IL13 (IL13 Antibody Abstract)
Background Interleukin 13 (IL-13), of the IL-4 superfamily, is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ra) and at least one IL-13-specific binding chain. Most of the biological effects of IL-13, like those of IL-4, are linked to a single transcription factor, STAT6. In humans, IL-13 can induce immunoglobulin E (IgE) secretion from activated B cells. In mice, deletion of IL-13 does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. Deletion of IL-4 abrogates these responses. IL-13 acts as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thus altering physiological function. Although IL-13 is associated primarily with the induction of airway disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, it also induces airway matrix metalloproteinases as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation.Synonyms: IL-13, NC30
Gene ID 396721
NCBI Accession NP_998968
UniProt Q95J68
Pathways JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport

Application Details

Product Details anti-IL-13 Antibody Target Details IL-13 Handling References for anti-IL-13 antibody (ABIN401064) Images back to top
Application Notes ELISA: 1/11,000. Western Blot: 1.5 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details References for anti-IL-13 antibody (ABIN401064) Images back to top
Format Liquid
Reconstitution Restore with 100 μL of deionized water or equivalent.
Concentration 1.0 mg/mL by UV absorbance at 280 nm
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-IL-13 antibody (ABIN401064)

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details Handling Images back to top
Background publications

Trigona, Brown, Estes: "Functional implications for signaling via the IL4R/IL13R complex on bovine cells." in: Veterinary immunology and immunopathology, Vol. 72, Issue 1-2, pp. 73-9, 2000

Images

Product Details anti-IL-13 Antibody Target Details IL-13 Application Details Handling References for anti-IL-13 antibody (ABIN401064) back to top
Supplier Images
 image for anti-Interleukin 13 (IL13) antibody (ABIN401064) anti-Interleukin 13 (IL13) antibody