anti-Mouse (Murine) IL-6 Receptor antibody for Immunohistochemistry (Frozen Sections)

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • IL6R
  • il-6ra
  • CD126
  • IL-6R-1
  • IL-6RA
  • IL6Q
  • IL6RA
  • IL6RQ
  • gp80
  • IL6R1
  • Il6ra
  • IL-6Ralpha
  • IL-6R
  • Il6r
  • interleukin 6 receptor
  • interleukin 6 receptor, alpha
  • IL6R
  • il6r
  • Il6r
  • Il6ra
Epitope
Extracellular Domain
23
19
17
15
10
7
7
6
6
6
5
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
184
87
45
1
Host
Rat
131
95
44
21
1
Clonality
Monoclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
26
15
15
10
9
8
6
6
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
132
121
102
71
39
24
24
22
17
13
10
10
9
8
8
6
4
2
2
2
2
2
1
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Catalog No. ABIN360909
$ 555.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN439445 IHC (fro) IHC WB Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606323 IHC IHC (fro) WB Alexa Fluor 700 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606324 IHC IHC (fro) WB Biotin Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606330 IHC IHC (fro) WB DyLight 680 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606322 IHC IHC (fro) WB Alexa Fluor 647 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606320 IHC IHC (fro) WB Alexa Fluor 405 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606321 IHC IHC (fro) WB Alexa Fluor 488 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606325 IHC IHC (fro) WB DyLight 350 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606327 IHC IHC (fro) WB DyLight 488 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606326 IHC IHC (fro) WB DyLight 405 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606329 IHC IHC (fro) WB DyLight 650 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606332 IHC IHC (fro) FITC Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606331 IHC IHC (fro) WB DyLight 755 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606328 IHC IHC (fro) WB DyLight 550 Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
1 ABIN5606333 IHC IHC (fro) WB HRP Rat IgG2 Extracellular Domain Log in to see RM0114-14F33

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Epitope Extracellular Domain
(23), (19), (17), (15), (10), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(184), (87), (45), (1)
Host Rat
(131), (95), (44), (21), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL-6 Receptor antibody is un-conjugated
(26), (15), (15), (10), (9), (8), (6), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(132), (121), (102), (71), (39), (24), (24), (22), (17), (13), (10), (10), (9), (8), (8), (6), (4), (2), (2), (2), (2), (2), (1)
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling Images
Specificity This antibody detects Mouse IL-6R. Other species not tested.
Purification Protein A/G affinity chromatography
Immunogen Recombinant protein of IL-6R extracellular domain.
Clone 14F33
Isotype IgG2

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD126 / IL6R (IL6R Antibody Abstract)
Background IL6 exerts its activity through binding to a high affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa IL6 binding receptor protein (IL6R) and a 130 kDa signal transducing protein consisting of a 19 amino acid residue signal peptide (gp130). Human IL6R is a 468 amino acid residue type I membrane protein consisting of a 19 amino acid residue signal peptide, a 339 residue extracellular region, a 28 residue transmembrane region and an 82 residue cytoplasmic region. The ectodomain of IL6R is made up of an immunoglobulin like domain and a cytokine receptor superfamily domain. A naturally occurring soluble form of the IL6R, which binds IL6 and which mediates IL6 signaling through interaction with gp130, is identified in the urine of healthy adult humans. It has also been detected in human and mouse serum as well as in the conditioned medium of various cells including human peripheral blood mononuclear cells, and several T cell or granulocyte/macrophage cell lines. Increased expression of the c-fos and c-myc protooncogenes have been linked to IL6 receptor activation.Synonyms: IL-6R 1, IL-6R-alpha, IL6 Receptor alpha, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80
Gene ID 16194
NCBI Accession NP_034689
UniProt P22272
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling, Autophagy, Growth Factor Binding

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Images back to top
Reconstitution Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.
Buffer PBS, None
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.