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anti-Mouse (Murine) IL-6 Receptor antibody for Immunohistochemistry (Frozen Sections)

Recommended IL-6 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin-6 Receptor (IL6R) Antibodies
  • CD126
  • gp80
  • IL-6R
  • IL-6R-1
  • IL-6RA
  • il-6ra
  • IL-6Ralpha
  • IL6Q
  • Il6r
  • IL6R
  • IL6R1
  • IL6RA
  • Il6ra
  • IL6RQ
Epitope
Extracellular Domain
13
13
6
6
5
5
5
5
5
4
4
4
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
131
57
43
Host
Rat
86
84
22
15
1
Clonality
Monoclonal
Conjugate
This IL-6 Receptor antibody is un-conjugated
22
14
11
10
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
86
76
73
27
21
15
12
12
11
11
10
9
8
6
4
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN360909
$ 555.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087814144 ABIN1859439 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 52-204 Log in to see Polyclonal
0.00087814144 ABIN439445 IHC (fro) IHC WB Rat IgG2 Extracellular Domain Log in to see RM0114-14F33
0.00087814144 ABIN1175054 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 205-347 Log in to see Polyclonal
0.00087814144 ABIN327366 FACS IHC (fro) ELISA WB Rat IgG2a Extracellular Domain Log in to see

Similar anti-IL-6 Receptor Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 2 Antibodies
ELISA 16 Antibodies
ELISA (Capture) 4 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 2 Antibodies
Flow Cytometry (FACS) 15 Antibodies
Functional Studies (Func) 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 19 Antibodies

General

Antigen Interleukin-6 Receptor (IL6R) Antibodies
Epitope Extracellular Domain
(13), (13), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(131), (57), (43)
Host Rat
(86), (84), (22), (15), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL-6 Receptor antibody is un-conjugated
(22), (14), (11), (10), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(86), (76), (73), (27), (21), (15), (12), (12), (11), (11), (10), (9), (8), (6), (4), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-IL-6 Receptor Antibody

Target Details IL-6 Receptor Application Details Handling Images
Specificity This antibody detects Mouse IL-6R. Other species not tested.
Purification Protein A/G affinity chromatography
Immunogen Recombinant protein of IL-6R extracellular domain.
Clone 14F33
Isotype IgG2

Target Details IL-6 Receptor

Product Details anti-IL-6 Receptor Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD126 / IL6R (IL6R Antibody Abstract)
Background IL6 exerts its activity through binding to a high affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa IL6 binding receptor protein (IL6R) and a 130 kDa signal transducing protein consisting of a 19 amino acid residue signal peptide (gp130). Human IL6R is a 468 amino acid residue type I membrane protein consisting of a 19 amino acid residue signal peptide, a 339 residue extracellular region, a 28 residue transmembrane region and an 82 residue cytoplasmic region. The ectodomain of IL6R is made up of an immunoglobulin like domain and a cytokine receptor superfamily domain. A naturally occurring soluble form of the IL6R, which binds IL6 and which mediates IL6 signaling through interaction with gp130, is identified in the urine of healthy adult humans. It has also been detected in human and mouse serum as well as in the conditioned medium of various cells including human peripheral blood mononuclear cells, and several T cell or granulocyte/macrophage cell lines. Increased expression of the c-fos and c-myc protooncogenes have been linked to IL6 receptor activation.Synonyms: IL-6R 1, IL-6R-alpha, IL6 Receptor alpha, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80
Gene ID 16194
NCBI Accession NP_034689
UniProt P22272
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL-6 Receptor Antibody Target Details IL-6 Receptor Application Details Images back to top
Reconstitution Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.
Buffer PBS, None
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.