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Human IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN417288
Wang, Hu, Wu, Zhao, Zhen, Wang, Li, Liang, Wu, Ma: The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma. in Gene 2016
Mouse (Murine) IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN425126
Sainoh, Orita, Miyagi, Sakuma, Yamauchi, Suzuki, Kubota, Oikawa, Inage, Sato, Fujimoto, Shiga, Inoue, Aoki, Takahashi, Ohtori: Interleukin-6 and interleukin-6 receptor expression, localization, and involvement in pain-sensing neuron activation in a mouse intervertebral disc injury model. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015
Human IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN857562
Sun, Long, Wu, Liu, Wang, Zhang, Wang, Hai: Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction. in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2015
Rat (Rattus) IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN367443
Saeed, El-Demerdash, Abdel-Rahman, Algandaby, Al-Abbasi, Abdel-Naim: Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. in Toxicology and applied pharmacology 2012
Mouse (Murine) IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN625411
Wu, Chai, Kim, Klein, Jordan: Monoclonal anti-interleukin-6 receptor antibody attenuates donor-specific antibody responses in a mouse model of allosensitization. in Transplant immunology 2013
Human IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN1055311
Zhang, Gao, Zhang, Jia, Wang, Zhang, Li: Alterations of IL-6, IL-6R and gp130 in early and late onset severe preeclampsia. in Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2013
The expression of IL-6, IL-6R and gp130 transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.
Data show that the let-7c/miR (show MLXIP ELISA Kits)-99a/miR (show MLXIP ELISA Kits)-125b cluster controlled tumorigenesis by targeting IL-6 (show IL6 ELISA Kits), IL-6R and IGF1R (show IGF1R ELISA Kits).
Our results argued that increased expression of sIL6R from myeloid cells and subsequent c-Maf (show MAF ELISA Kits) induction were adverse events for counteracting tumor-specific Th1 (show TH1L ELISA Kits) generation. Overall, this work provides a mechanistic rationale for sIL6R targeting to improve the efficacy of T-cell-mediated cancer immunotherapy
These results demonstrate a novel physiologic role for a disintegrin and metalloprotease 17 (show ADAM17 ELISA Kits) in regulating murine IL-6 (show IL6 ELISA Kits) signals during inflammatory processes.
this study show that soluble IL-6R is infiltrating from the circulation in an ADAM17 (show ADAM17 ELISA Kits)-independent process and is involved in the controlled resolution of an acute inflammatory episode
the sIL (show PMEL ELISA Kits)-6R/p28 (show PSMD10 ELISA Kits) fusion protein (FP) upregulated IFN-lambda1 expression by increasing the binding abilities of c-Fos and activating transcription factor 1 (show AFT1 ELISA Kits) to the IFN-lambda1 promoter via the p38 MAPK (show MAPK14 ELISA Kits) signaling pathway; results demonstrate the important role of sIL (show PMEL ELISA Kits)-6R/p28 (show PSMD10 ELISA Kits) FP in mediating virus-induced type III IFN production
Thus, trans-signaling of IL-6 (show IL6 ELISA Kits) can only occur via sIL (show PMEL ELISA Kits)-6R, but not sCD5 (show SCD5 ELISA Kits).
The here presented data demonstrate that miR (show MLXIP ELISA Kits)-451 may function as a potential suppressor of tumor growth, migration and angiogenesis in osteosarcoma via down-regulating IL 6R.
DNA hypomethylation of IL-6 (show IL6 ELISA Kits) gene measured in blood leukocytes was associated with increased risk of ischemic heart disease.
minor allele, with the difference eliminated upon addition of tocilizumab. In conclusion, there is evidence that neutrophils may be an important source of sIL (show PMEL ELISA Kits)-6R in the lungs, and the Asp358Ala variant may have pro-inflammatory effects in lung cells.d However, we were unable to identify evidence for aisease
IL-6sR and gp130 (show ANPEP ELISA Kits), but not IL-6R alpha, play important roles in regulation of granulosa cell survival
Mechanical injury potentiates the catabolic effects of TNFalpha (show TNF ELISA Kits) and IL-6 (show IL6 ELISA Kits)/sIL (show STIL ELISA Kits)-6R in causing proteoglycan (show Vcan ELISA Kits) degradation in human and bovine cartilage.
TNF (show TNF ELISA Kits)/IL-6 (show IL6 ELISA Kits) generated osteoclasts in vitro that resorbed mineralized tissue through a pathway dependent on IL-6R, NFATc1 (show NFATC1 ELISA Kits), DNAX-activation protein 12 (show TYROBP ELISA Kits), and cell proliferation
C2C12 myotubes possesses a mechanism for regulating IL-6R and gp130 expression following lipoic acid treatment or heat shock.
Interleukin-6 receptor alpha may have a role in skin lesions in a murine model of systemic lupus erythematosus
findings identify TRAF3 (show TRAF3 ELISA Kits) and PTPN22 (show PTPN22 ELISA Kits) as inhibitors of IL-6R signaling in B cells and reveal a previously uncharacterized role for TRAF3 (show TRAF3 ELISA Kits) in the regulation of plasma cell differentiation
Data show that blockade of interleukin-6 receptor by an anti-IL-6R antibody can augment the anti-arthritic effect of glucocorticoids (GCs (show UGCG ELISA Kits)) and inhibit the bone loss they cause.
established that endogenous IL-6R of both human and murine origin is shed by ADAM17 (show ADAM17 ELISA Kits) in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10 (show ADAM10 ELISA Kits)
Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorgammaT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung
When endogenously released IL-6 (show IL6 ELISA Kits) binds to Il-6Ralpha in brain the effect is pyrogenic.
metastasizing cancer cells induced higher MDSCs infiltration and prompted them to secret exaggerated IL-6 (show IL6 ELISA Kits) as well as soluble IL-6Ra, which, in turn, triggered a persistent increase of pSTAT3 in tumor cells.
Cellular senescence or EGFR (show EGFR ELISA Kits) signaling induces Interleukin 6 receptor expression controlled by mTOR (show FRAP1 ELISA Kits).
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
interleukin 6 receptor
, interleukin 6 receptor alpha
, interleukin-6 receptor subunit alpha
, CD126 antigen
, IL-6 receptor subunit alpha
, IL-6R 1
, membrane glycoprotein 80
, IL-6R subunit alpha
, interleukin 6 receptor, alpha
, IL-6 receptor alpha chain