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Mouse (Murine) IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN625411
Wu, Chai, Kim, Klein, Jordan: Monoclonal anti-interleukin-6 receptor antibody attenuates donor-specific antibody responses in a mouse model of allosensitization. in Transplant immunology 2013
Rat (Rattus) IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN367443
Saeed, El-Demerdash, Abdel-Rahman, Algandaby, Al-Abbasi, Abdel-Naim: Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. in Toxicology and applied pharmacology 2012
Human IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN857562
Sun, Long, Wu, Liu, Wang, Zhang, Wang, Hai: Effect of alcohol on diethylnitrosamine-induced hepatic toxicity: Critical role of ROS, lipid accumulation, and mitochondrial dysfunction. in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2015
Human IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN417288
Wang, Hu, Wu, Zhao, Zhen, Wang, Li, Liang, Wu, Ma: The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma. in Gene 2016
Mouse (Murine) IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN425126
Sainoh, Orita, Miyagi, Sakuma, Yamauchi, Suzuki, Kubota, Oikawa, Inage, Sato, Fujimoto, Shiga, Inoue, Aoki, Takahashi, Ohtori: Interleukin-6 and interleukin-6 receptor expression, localization, and involvement in pain-sensing neuron activation in a mouse intervertebral disc injury model. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015
Human IL-6 Receptor ELISA Kit for Sandwich ELISA - ABIN1055311
Zhang, Gao, Zhang, Jia, Wang, Zhang, Li: Alterations of IL-6, IL-6R and gp130 in early and late onset severe preeclampsia. in Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2013
The expression of IL-6, IL-6R and gp130 transcripts were detected very early, increased during the first week of life and were predominantly expressed in the head, epidermis and neuromasts of the anterior and posterior lateral line system.
The sgp130, IL-6 (show IL6 ELISA Kits), and sIL (show PMEL ELISA Kits)-6R concentrations were statistically significantly elevated in patients with diabetic retinopathy (DR), suggesting a probable contributing role of the IL-6 (show IL6 ELISA Kits) trans-signaling pathway to the pathophysiology of DR.
The mRNA expression of IL6R was inversely correlated with miR (show MLXIP ELISA Kits)-449a in osteosarcoma tissues. In addition, JAK1 (show JAK1 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) signaling pathway was regulated by circ_0009910/miR (show MLXIP ELISA Kits)-449a/IL6R axis.
IL-6 receptor blockade has an effect on high-sensitivity troponin T and NT-proBNP in rheumatoid arthritis
study demonstrates enhanced T cell responses to IL-6 (show IL6 ELISA Kits) in T1D due, in part, to an increase in IL-6R surface expression. Dysregulated IL-6 (show IL6 ELISA Kits) responsiveness may contribute to diabetes through multiple mechanisms including altered T cell trafficking
Enterovirus 71 antagonizes the antiviral activity of host STAT3 (show STAT3 ELISA Kits) and IL-6R with partial dependence on virus-induced miR (show MLXIP ELISA Kits)-124.
we present evidence for the role of M2 phenotype TAM (show CCNA1 ELISA Kits) in IL-6 (show IL6 ELISA Kits) receptor-mediated signals, particularly tyrosine phosphorylation of STAT3 (show STAT3 ELISA Kits), responsible for the prosurvival adaptation of tumor cells to hypoxia.
3 SNPs (rs4329505 and rs4845626 in interleukin 6 receptor (show IL6ST ELISA Kits) [IL6R] and rs1422794 in a disintegrin and metalloproteinase domain 19 [ADAM19 (show Adam19 ELISA Kits)]) were associated with a lower risk of suffering the most severe stages of the disease.
The expression of STOML2, a gene that plays a key role in mitochondrial function and T-cell activation, is associated with both IL-6 (show IL6 ELISA Kits) signaling and asthma risk.
IL6R is downregulated in the tissues from colonic biopsies taken from Ulcerative Colitis patients.Thus, expression levels of IL6R can be used as markers of disease or disease progression in Ulcerative Colitis patients.
expanded CD8 (show CD8A ELISA Kits)(+)IL-6Ralpha(low) EM T cells have roles in coronary artery disease through their pro-inflammatory and highly cytotoxic capacities
IL-6sR and gp130 (show ANPEP ELISA Kits), but not IL-6R alpha, play important roles in regulation of granulosa cell survival
Mechanical injury potentiates the catabolic effects of TNFalpha (show TNF ELISA Kits) and IL-6 (show IL6 ELISA Kits)/sIL (show STIL ELISA Kits)-6R in causing proteoglycan (show Vcan ELISA Kits) degradation in human and bovine cartilage.
TNF (show TNF ELISA Kits)/IL-6 (show IL6 ELISA Kits) generated osteoclasts in vitro that resorbed mineralized tissue through a pathway dependent on IL-6R, NFATc1 (show NFATC1 ELISA Kits), DNAX-activation protein 12 (show TYROBP ELISA Kits), and cell proliferation
C2C12 myotubes possesses a mechanism for regulating IL-6R and gp130 expression following lipoic acid treatment or heat shock.
Interleukin-6 receptor alpha may have a role in skin lesions in a murine model of systemic lupus erythematosus
findings identify TRAF3 (show TRAF3 ELISA Kits) and PTPN22 (show PTPN22 ELISA Kits) as inhibitors of IL-6R signaling in B cells and reveal a previously uncharacterized role for TRAF3 (show TRAF3 ELISA Kits) in the regulation of plasma cell differentiation
Data show that blockade of interleukin-6 receptor by an anti-IL-6R antibody can augment the anti-arthritic effect of glucocorticoids (GCs (show UGCG ELISA Kits)) and inhibit the bone loss they cause.
established that endogenous IL-6R of both human and murine origin is shed by ADAM17 (show ADAM17 ELISA Kits) in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10 (show ADAM10 ELISA Kits)
Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorgammaT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung
When endogenously released IL-6 (show IL6 ELISA Kits) binds to Il-6Ralpha in brain the effect is pyrogenic.
metastasizing cancer cells induced higher MDSCs infiltration and prompted them to secret exaggerated IL-6 (show IL6 ELISA Kits) as well as soluble IL-6Ra, which, in turn, triggered a persistent increase of pSTAT3 in tumor cells.
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
interleukin 6 receptor
, interleukin 6 receptor alpha
, interleukin-6 receptor subunit alpha
, CD126 antigen
, IL-6 receptor subunit alpha
, IL-6R 1
, membrane glycoprotein 80
, IL-6R subunit alpha
, interleukin 6 receptor, alpha
, IL-6 receptor alpha chain