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|Antigen||Interleukin 11 (IL11) Antibodies|
|Epitope||AA 22-199 Alternatives|
|Conjugate||This IL11 antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-IL11 AntibodyTarget Details IL11 Application Details Handling References for anti-IL11 antibody (ABIN4899646) Images
|Specificity||Detects human IL-11 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100 % cross-reactivity with recombinant mouse IL-11 is observed and no cross-reactivity with recombinant human (rh) IL-6, rhCNTF, rhLIF, rhOSM, rhCLC, or rhCT-1 is observed.|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Sterility||0.2 μm filtered|
|Endotoxin Level||<0.10 EU per 1 μg of the antibody by the LAL method.|
|Immunogen||E. coli-derived recombinant human IL-11, Pro22-Leu199, Accession # P20809|
Target Details IL11Product Details anti-IL11 Antibody Application Details Handling References for anti-IL11 antibody (ABIN4899646) Images back to top
|Alternative Name||IL-11 (IL11 Antibody Abstract)|
|Pathways||JAK-STAT Signaling, Negative Regulation of Hormone Secretion|
Application DetailsProduct Details anti-IL11 Antibody Target Details IL11 Handling References for anti-IL11 antibody (ABIN4899646) Images back to top
|Application Notes||Western Blot 1 μg/mL, Neutralization 5-15 μg/mL, Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells, CyTOF-ready|
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL11 Antibody Target Details IL11 Application Details References for anti-IL11 antibody (ABIN4899646) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C/-20 °C/-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-IL11 antibody (ABIN4899646)Product Details anti-IL11 Antibody Target Details IL11 Application Details Handling Images back to top
|Product cited in:||
Zhou, Ji, Cai, Shi, Chen, Yu, Zhu, Zhang: "MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11." in: BMC cancer, Vol. 15, pp. 343, 2015 Method employed by authors: Neutralization (Neut) (Sample species: Human).
Bockhorn, Dalton, Nwachukwu, Huang, Prat, Yee, Chang, Huo, Wen, Swanson, Qiu, Lu, Park, Dolan, Perou, Olopade, Clarke, Greene, Liu: "MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11." in: Nature communications, Vol. 4, pp. 1393, 2013 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Kim, Kim, Ham, Brown, Greene, DAgati, Lee: "IL-11 is required for A1 adenosine receptor-mediated protection against ischemic AKI." in: Journal of the American Society of Nephrology : JASN, Vol. 24, Issue 10, pp. 1558-70, 2013 Method employed by authors: Neutralization (Neut) (Sample species: Human).
ImagesProduct Details anti-IL11 Antibody Target Details IL11 Application Details Handling References for anti-IL11 antibody (ABIN4899646) back to top