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anti-Mouse (Murine) IL12RB2 antibody for ELISA

Recommended IL12RB2 Antibody (supplied by: Log in to see )

Antigen
Interleukin 12 Receptor, beta 2 (IL12RB2) Antibodies
  • IL12RB2
  • A930027I18Rik
  • IL-12RB2
  • Ifnm
  • interleukin 12 receptor, beta 2
  • IL12RB2
  • Il12rb2
Epitope
AA 1-637
17
15
10
10
8
6
5
5
4
3
3
2
2
1
1
1
1
1
Reactivity
Mouse (Murine)
76
37
18
Host
Rabbit
66
22
Clonality
Monoclonal
Conjugate
This IL12RB2 antibody is un-conjugated
7
6
6
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA
50
31
28
22
13
8
4
4
2
1
Supplier
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Supplier Product No.
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Catalog No. ABIN2000353
$ 273.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2623877 ELISA WB Biotin Rabbit IgG AA 455-606 Log in to see Polyclonal
1 ABIN2623875 ELISA WB Biotin Rabbit IgG AA 285-441 Log in to see Polyclonal
1 ABIN2434812 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN2433183 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN2623873 ELISA Rabbit IgG AA 285-441 Log in to see Polyclonal
1 ABIN2623874 ELISA Rabbit IgG AA 455-606 Log in to see Polyclonal
1 ABIN2214135 ELISA Rabbit Log in to see Polyclonal

Similar anti-IL12RB2 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 8 Antibodies
Flow Cytometry (FACS) 8 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Interleukin 12 Receptor, beta 2 (IL12RB2) Antibodies
Epitope AA 1-637
(17), (15), (10), (10), (8), (6), (5), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(76), (37), (18)
Host Rabbit
(66), (22)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL12RB2 antibody is un-conjugated
(7), (6), (6), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA
(50), (31), (28), (22), (13), (8), (4), (4), (2), (1)
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Product Details anti-IL12RB2 Antibody

Target Details IL12RB2 Application Details Handling Images
Specificity Mouse IL12RB2
Sensitivity 0.0195 ng/well
Characteristics This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL12RB2 (rM IL12RB2, NP_032380.1, Met1-Asn637).
Sterility 0.2 μm filtered
Immunogen Recombinant Mouse IL12RB2 protein
Clone 93
Isotype IgG

Target Details IL12RB2

Product Details anti-IL12RB2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL12RB2 (IL12RB2 Antibody Abstract)
Background Interleukin-12 receptor subunit beta-2, also known as IL-12 receptor subunit beta-2, IL-12R- beta-2 and IL12RB2, is a single-pass type I membrane protein which belongs to thetype I cytokine receptor family and type 2 subfamily. IL12RB2 contains fivefibronectin type-III domains. IL12RB2 is a receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. IL12RB2 promotes the proliferation of T-cells as well as NK cells. It induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. The functional high affinity IL12 receptor is composed of I12RB1 and IL12RB2. Il12RB2 binds JAK2 (via its N-terminal) through a membrane- proximal region of the cytoplasmic domain. Interaction, in vitro and in vivo, with SOCS3 (via its SH2 domain) inhibits the STAT4-mediated activation. Il12RB2 binds STAT4 through a membrane-distal C-terminal region. The WSXWS motif of Il12RB2 appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box one motif of Il12RB2 is required for JAK interaction and/or activation.
NCBI Accession NP_032380.1
Research Area Cancer, Cytokines, Innate Immunity
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL12RB2 Antibody Target Details IL12RB2 Handling Images back to top
Application Notes Direct ELISA - This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse IL12Rb2. The detection limit for Mouse IL12Rb2 is approximately 0.0195 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IL12RB2 Antibody Target Details IL12RB2 Application Details Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months