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anti-Human IL2 Receptor beta antibody for Neutralization

Recommended IL2 Receptor beta Antibody (supplied by: Log in to see )

Antigen
Interleukin 2 Receptor, beta (IL2RB) Antibodies
  • IL2RB
  • il-2rb
  • CD122
  • IL15RB
  • P70-75
  • IL2RBC
  • IL-15Rbeta
  • IL15Rbeta
  • Il-2/15Rbeta
  • Il-2Rbeta
  • p70
  • interleukin 2 receptor, beta
  • interleukin-2 receptor subunit beta-like
  • interleukin 2 receptor, beta chain
  • IL2RB
  • LOC510185
  • il2rb
  • Il2rb
  • LOC100621776
  • LOC100859707
Epitope
AA 27-239
29
17
14
8
5
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
213
154
92
29
6
1
1
Host
Mouse
135
118
82
Clonality
Monoclonal
Conjugate
This IL2 Receptor beta antibody is un-conjugated
34
30
19
9
9
9
6
6
6
6
6
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)
212
96
53
45
32
26
13
10
8
6
5
4
3
3
2
2
1
1
1
Supplier
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Catalog No. ABIN4900009
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
36.14423 ABIN4900010 FACS IHC Neut Mouse IgG1 AA 27-239 Log in to see 27302 5
1 ABIN1983280 Neut IHC WB Mouse IgG1 AA 27-239 Log in to see MM0392-1Y60

Top referenced anti-IL2 Receptor beta antibody for Neutralization

Similar anti-IL2 Receptor beta Antibodies

Application / Reactivity Human
ELISA 33 Antibodies
Flow Cytometry (FACS) 53 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 10 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 24 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Multiplex Assay (MA) 1 Antibodies
Neutralization (Neut) 3 Antibodies
Western Blotting (WB) 79 Antibodies

General

Antigen Interleukin 2 Receptor, beta (IL2RB) Antibodies
Epitope AA 27-239
(29), (17), (14), (8), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(213), (154), (92), (29), (6), (1), (1)
Host Mouse
(135), (118), (82)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL2 Receptor beta antibody is un-conjugated
(34), (30), (19), (9), (9), (9), (6), (6), (6), (6), (6), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (IHC), Neutralization (Neut)
(212), (96), (53), (45), (32), (26), (13), (10), (8), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-IL2 Receptor beta Antibody

Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN4900009) Images
Specificity Detects human IL-2 R beta in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rh gamma c, rhIL-4 R, or rhIL-6 R is observed.
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-2 R beta , Ala27-Asp239, Accession # NP_000869
Clone 27302
Isotype IgG1

Target Details IL2 Receptor beta

Product Details anti-IL2 Receptor beta Antibody Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN4900009) Images back to top
Antigen
Alternative Name IL-2 R beta (IL2RB Antibody Abstract)
Background Alternative Names: CD122, CD122 antigen, high affinity IL-2 receptor beta subunit, High affinity IL-2 receptor subunit beta, IL-15 R beta, IL-2 receptor subunit beta, IL2R beta, IL-2R subunit beta, IL2RB, IL-2RB, interleukin 15 receptor, beta, interleukin 2 receptor, beta, interleukin-2 receptor subunit beta, P70-75, p75
Gene ID 3560
NCBI Accession NP_000869
Research Area Immunology
Pathways JAK-STAT Signaling, Growth Factor Binding

Application Details

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Handling References for anti-IL2 Receptor beta Antibody (ABIN4900009) Images back to top
Application Notes Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 8-25 μg/mL
Neutralization 0.05-0.15 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details References for anti-IL2 Receptor beta Antibody (ABIN4900009) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL2 Receptor beta Antibody (ABIN4900009)

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling Images back to top
Product cited in:

Jiang, Chen, An, Yang, Zhang, Cheng: "Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling." in: Scientific reports, Vol. 6, pp. 32320, 2016 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ndhlovu, Leal, Eccles-James, Jha, Lanteri, Norris, Barbour, Wachter, Andersson, Taskén, Torheim, Aandahl, Kallas, Nixon: "A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties." in: European journal of immunology, Vol. 40, Issue 1, pp. 134-41, 2010 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Rose, Lambotte, Pallier, Delfraissy, Colle: "Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7389-97, 2009 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Eberly, Kader, Hassan, Rogers, Zhou, Mueller, Mattapallil, Piatak, Lifson, Katsikis, Roederer, Villinger, Mattapallil: "Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1439-48, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Rhesus Monkey).

Miranda-Carús, Balsa, Benito-Miguel, Pérez de Ayala, Martín-Mola: "IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 2, pp. 1463-76, 2004 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Images

Product Details anti-IL2 Receptor beta Antibody Target Details IL2 Receptor beta Application Details Handling References for anti-IL2 Receptor beta Antibody (ABIN4900009) back to top
Supplier Images
Neutralization (Neut) image for anti-IL2 Receptor beta antibody (Interleukin 2 Receptor, beta) (AA 27-239) (ABIN4900009) Cell Proliferation Induced by IL-2 and Neutralization by Human IL-2 R beta Antibody. ...
Immunohistochemistry (IHC) image for anti-IL2 Receptor beta antibody (Interleukin 2 Receptor, beta) (AA 27-239) (ABIN4900009) IL-2 R beta in Human Lymph Node. IL-2 R beta was detected in immersion fixed frozen s...