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anti-Mouse (Murine) IL21 Receptor antibody for Blocking Reagent

Recommended IL21 Receptor Antibody (supplied by: Log in to see )

Antigen
Interleukin 21 Receptor (IL21R) Antibodies
  • CD360
  • il-21ra.a
  • IL21R
  • NILR
Reactivity
Mouse (Murine)
92
49
30
2
Host
Rat
71
22
14
6
Clonality
Monoclonal
Conjugate
This IL21 Receptor antibody is conjugated to PE
7
6
6
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS)
52
38
28
21
13
11
4
4
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN2663782
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008711731 ABIN2663783 BR FACS PE Rat IgG2a kappa Log in to see 4A9 4

Top referenced anti-IL21 Receptor antibody for Blocking Reagent

Similar anti-IL21 Receptor Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 2 Antibodies
ELISA 16 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 15 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 12 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Western Blotting (WB) 21 Antibodies

General

Antigen Interleukin 21 Receptor (IL21R) Antibodies
Reactivity Mouse (Murine)
(92), (49), (30), (2)
Host Rat
(71), (22), (14), (6)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL21 Receptor antibody is conjugated to PE
(7), (6), (6), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS)
(52), (38), (28), (21), (13), (11), (4), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-IL21 Receptor Antibody

Target Details IL21 Receptor Application Details Handling References for anti-IL21 Receptor Antibody (ABIN2663782) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone 4A9
Isotype IgG2a kappa

Target Details IL21 Receptor

Product Details anti-IL21 Receptor Antibody Application Details Handling References for anti-IL21 Receptor Antibody (ABIN2663782) Images back to top
Antigen
Alternative Name IL-21 Receptor (IL21R Antibody Abstract)
Background The IL-21R is a member of the cytokine receptor family that closely resembles IL-2R beta and IL-4R alpha. IL-21R is expressed by all mature lymphocytes and up-regulated after B and/or T cell activation, with the highest expression by activated B cells. A functional IL-21R consists of the IL-21R subunit and the commone gamma-chaiin. Upon binding to IL-21, it activates Jak-1, Jak-3, STAT1, STAT3 and STAT 5 transduction pathway.
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Handling References for anti-IL21 Receptor Antibody (ABIN2663782) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details References for anti-IL21 Receptor Antibody (ABIN2663782) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL21 Receptor Antibody (ABIN2663782)

Product Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details Handling Images back to top
Background publications

McPhee, Bubier, Sproule, Park, Steinbuck, Schott, Christianson, Morse, Roopenian: "IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 9, pp. 4581-8, 2013

Jin, Malek: "Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21." in: Journal of leukocyte biology, Vol. 80, Issue 6, pp. 1416-23, 2006

Mehta, Wurster, Grusby: "Biology of IL-21 and the IL-21 receptor." in: Immunological reviews, Vol. 202, pp. 84-95, 2004

Jin, Carrio, Yu, Malek: "Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 1, pp. 657-65, 2004

Images

Product Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details Handling References for anti-IL21 Receptor Antibody (ABIN2663782) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL21 Receptor antibody (Interleukin 21 Receptor)  (PE) (ABIN2663782) anti-Interleukin 21 Receptor (IL21R) antibody (PE)