We are preparing the requested document. Please wait, this may take a while...!
|Antigen||Interleukin 21 Receptor (IL21R) Antibodies|
|Epitope||AA 20-32 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This IL21 Receptor antibody is un-conjugated Alternatives|
Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-IL21 Receptor AntibodyTarget Details IL21 Receptor Application Details Handling Images
|Immunogen||Synthetic peptide corresponding to amino acids 20-32 of human IL-21 receptor. AA Sequence:CPDLVCYTDYLQT|
Target Details IL21 ReceptorProduct Details anti-IL21 Receptor Antibody Application Details Handling Images back to top
|Alternative Name||Interleukin-21 Receptor / IL21R (IL21R Antibody Abstract)|
|Background||IL21 Receptor is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.Synonyms: IL-21R, IL21 receptor, NILR, Novel interleukin receptor|
Application DetailsProduct Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Handling Images back to top
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details Images back to top
|Buffer||PBS containing 0.02 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
|Expiry Date||12 months|
ImagesProduct Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details Handling back to top