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the oncogenic events of FLT3 (show FLT3 ELISA Kits)/ITD happen at a cell stage possessing CD123
IL-3 (show IL-3 ELISA Kits) hardly down-regulates the alpha-chain (show FCGRT ELISA Kits) of its receptor without depleting the common beta-chain (show CSF2RB ELISA Kits), which enables extraordinarily sustained signaling events, predominantly the activation of Stat5 (show STAT5A ELISA Kits).
Data indicate that CD123 was preferentially expressed among CD33 (show CD33 ELISA Kits)/CD117-positive precursor-T-acute lymphoblastic leukemia (T-ALL).
CD123 positivity represents a marker that can facilitate identification of the early T-cell precursor leukemia subtype, but the lack of sensitivity by immunohistochemistry limits the diagnostic utility.
CD123 expression is associated with systemic mastocytosis.
Our results suggest that the CD34 (show CD34 ELISA Kits)/CD25 (show IL2RA ELISA Kits)/CD123/CD99 (show CD99 ELISA Kits)(+) LAIP is strictly associated with FLT3 (show FLT3 ELISA Kits)-ITD-positive cells.
Human BDCA2+CD123+CD56 (show NCAM1 ELISA Kits)+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset.
CD96 (show CD96 ELISA Kits) and CD123 are expressed in bone marrow cells of patients with myelodysplastic syndromes
High interleukin-3 receptor alpha is associated with blastic plasmacytoid dendritic cell neoplasm.
High CD123 expression is associated with systemic mastocytosis.
expression of the interleukin 3 receptor alpha (Il3ra also known as Cd123) subunit is dependent on Jmjd2 (show KDM4A ELISA Kits)/Kdm4 through a mechanism involving removal of H3K9me3 from the promoter of the Il3ra gene.
Data indicate that the proliferative and differentiative effect of saponins from Sanguisorba officinalis (DYS (show DHPS ELISA Kits)) on megakaryocyte progenitor cells is correlated to the up-regulation of IL-3 (show IL-3 ELISA Kits) receptor and c-kit (show KIT ELISA Kits) expression.
Findings indicate that SLP-76 (show LCP2 ELISA Kits) is an essential signaling component for basophil activation downstream of both FcepsilonRI (show FCER1A ELISA Kits) and the IL-3 (show IL-3 ELISA Kits) receptor.
Interleukin-3 (show IL-3 ELISA Kits)/dendritic cells expressed higher levels of interleukin-3 (show IL-3 ELISA Kits) receptor.
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
cytokine receptor-like protein CYRL
, interleukin 3 receptor, alpha chain
, interleukin-3 receptor subunit alpha
, CD123 antigen
, IL-3 receptor alpha SP2 isoform
, IL-3 receptor subunit alpha
, IL-3R subunit alpha
, IL-3 receptor alpha chain
, Il-3 alpha subunit
, interleukin-3 receptor class II alpha chain