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|Application / Reactivity||Human|
|Blocking Antibody (Inhibition)||6 Antibodies|
|ELISA (Capture)||4 Antibodies|
|ELISA (Detection)||3 Antibodies|
|ELISpot (Capture) (ELISPOT (Capture))||1 Antibodies|
|ELISpot (Detection) (ELISPOT (Detection))||1 Antibodies|
|Enzyme Immunoassay (EIA)||7 Antibodies|
|Flow Cytometry (FACS)||33 Antibodies|
|Functional Studies (Func)||9 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||6 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||16 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies|
|Antigen||Interleukin 5 (IL5) Antibodies|
|Conjugate||This IL5 antibody is conjugated to PE Alternatives|
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
|9 references available|
|Supplier||Log in to see|
Product Details anti-IL5 AntibodyTarget Details IL5 Application Details Handling References for anti-IL5 Antibody (ABIN2663800) Images
|Cross-Reactivity||Cynomolgus, Rhesus Monkey|
|Purification||The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.|
Target Details IL5Product Details anti-IL5 Antibody Application Details Handling References for anti-IL5 Antibody (ABIN2663800) Images back to top
|Alternative Name||IL-5 (IL5 Antibody Abstract)|
|Background||IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70 % identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. The JES1-39D10 antibody can neutralize the bioactivity of natural or recombinant IL-5.|
|Research Area||Cytokines, Immunology, Virology, Inflammation, Cancer|
Application DetailsProduct Details anti-IL5 Antibody Target Details IL5 Handling References for anti-IL5 Antibody (ABIN2663800) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL5 Antibody Target Details IL5 Application Details References for anti-IL5 Antibody (ABIN2663800) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Protect from prolonged exposure to light. Do not freeze.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-IL5 Antibody (ABIN2663800)Product Details anti-IL5 Antibody Target Details IL5 Application Details Handling Images back to top
Norrgren, Bamba, da Silva et al.: "High mortality and severe immunosuppression in hospitalized patients with pulmonary tuberculosis and HIV-2 infection in Guinea-Bissau." in: Scandinavian journal of infectious diseases, Vol. 33, Issue 6, pp. 450-6, 2001 (PubMed).
Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).
Takatsu, Tominaga, Harada et al.: "T cell-replacing factor (TRF)/interleukin 5 (IL-5): molecular and functional properties." in: Immunological reviews, Vol. 102, pp. 107-35, 1988 (PubMed).
Limaye, Abrams, Silver et al.: "Interleukin-5 and the posttreatment eosinophilia in patients with onchocerciasis." in: The Journal of clinical investigation, Vol. 88, Issue 4, pp. 1418-21, 1991 (PubMed).
Takatsu: "Interleukin 5 (IL-5) and its receptor." in: Microbiology and immunology, Vol. 35, Issue 8, pp. 593-606, 1992 (PubMed).
Butterfield, Leiferman, Abrams et al.: "Elevated serum levels of interleukin-5 in patients with the syndrome of episodic angioedema and eosinophilia." in: Blood, Vol. 79, Issue 3, pp. 688-92, 1992 (PubMed).
Takatsu: "Interleukin-5." in: Current opinion in immunology, Vol. 4, Issue 3, pp. 299-306, 1992 (PubMed).
Abrams, Roncarolo, Yssel et al.: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).
Mahanty, Abrams, King et al.: "Parallel regulation of IL-4 and IL-5 in human helminth infections." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 11, pp. 3567-71, 1992 (PubMed).
ImagesProduct Details anti-IL5 Antibody Target Details IL5 Application Details Handling References for anti-IL5 Antibody (ABIN2663800) back to top