Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human Oncostatin M Receptor Protein expressed in Human Cells - ABIN2004128
Mosley, De Imus, Friend, Boiani, Thoma, Park, Cosman: Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. in The Journal of biological chemistry 1997
Show all 2 references for ABIN2004128
Mouse (Murine) Oncostatin M Receptor Protein expressed in Human Cells - ABIN2007899
Radtke, Hermanns, Haan, Schmitz-Van De Leur, Gascan, Heinrich, Behrmann: Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression. in The Journal of biological chemistry 2002
Show all 2 references for ABIN2007899
OSM:OSMR interactions are able to induce EMT (show ITK Proteins), increased cancer stem cell-like properties and enhanced lung colonisation in SCC (show CYP11A1 Proteins) cells
the RET (show RET Proteins) p.S891A mutation combined with OSMR p.G513D may underlie a novel phenotype manifesting as familial medullary thyroid carcinoma and cutaneous amyloidosis
this study offers new findings on the molecular genetics and disease relevance of mutations in OSMR in Familial primary localized cutaneous amyloidosis.
Oncostatin M (show OSM Proteins) and interleukin-31 (show IL31 Proteins): Cytokines, receptors, signal transduction and physiology.
primary localized cutaneous amyloidosis has a missense mutation in oncostatin M receptor beta
The interleukin IL-31 (show IL31 Proteins)/IL-31receptor axis contributes to tumor growth in human follicular lymphoma.
oncostatin M (show OSM Proteins) is a cytokine possessing vigorous antiviral and immunostimulatory properties which is released by APC (show APC Proteins) upon interaction with CD40L (show CD40LG Proteins) present on activated CD4 (show CD4 Proteins)+ T cells.
The disease severity of rheumatoid arthritis and systemic lupus erythematosus can be partially affected by the OSMR promoter polymorphisms.
We conclude that an OSMR/TGM2 (show TGM2 Proteins)/integrin-alpha5beta1/fibronectin (show FN1 Proteins) pathway is of biological significance in cervical squamous cell carcinoma
A unique loop structure in oncostatin M (show OSM Proteins) determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor (show LIFR Proteins).
In astrocytes but not microglia, phosphorylation of STAT1 (show STAT1 Proteins) and STAT3 (show STAT3 Proteins) occurred in response to OSM (show OSM Proteins), whereas both microglia and astrocytes responded to hyper-IL-6 (IL-6 (show IL6 Proteins) linked to the soluble IL-6 (show IL6 Proteins) receptor).
OSM (show OSM Proteins) signaling via OSMR in synovial fibroblasts has the potential to contribute significantly to joint destruction in inflammatory arthritis.
defects in OSM (show OSM Proteins) signaling promote the deterioration of high-fat diet-induced obesity and related metabolic disorders
Data indicate that OSM (show OSM Proteins) receptor beta subunit (show POLG Proteins)-deficient (OSMRbeta(-/-)) mice exhibited phenotypic changes in adipose tissue macrophages (ATMs) to M1, increased proinflammatory cytokines in the adipose tissue, and systemic insulin (show INS Proteins) resistance.
These data indicate that the transient RANKL (show TNFSF11 Proteins) induction by intermittent PTH (show PTH Proteins) administration, which is associated with its anabolic action, is changed to a prolonged induction in OSMR-deficient osteoblasts, resulting in bone destruction.
Bone formation can be stimulated independently of bone resorption and provide new insights into OSMR signaling.
Expression of oncostatin M receptor beta in a specific subset of nociceptive sensory neurons.
Mice deficient in OSM (show OSM Proteins) receptor showed impaired liver regeneration with persistent parenchymal necrosis after carbon tetrachloride exposure. Recovery of liver mass from partial hepatectomy was also significantly delayed in OSMR(-/-) mice.
the up-regulation of p-STAT3 (show STAT3 Proteins) and p-CREB (show CREB1 Proteins) may be induced possibly through OSMR in inflammation
This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
IL-31 receptor subunit beta
, IL-31R subunit beta
, interleukin-31 receptor subunit beta
, oncostatin-M specific receptor beta subunit
, oncostatin-M-specific receptor subunit beta
, oncostatin receptor
, oncostatin-M specific receptor subunit beta
, oncostatin M specific receptor