anti-Mouse (Murine) Serotonin Receptor 1A antibody for Immunoprecipitation

Recommended Serotonin Receptor 1A Antibody (supplied by: Log in to see )

Antigen
Serotonin Receptor 1A (HTR1A) Antibodies
  • 5-HT-dro2A
  • 5-HT1ADro
  • 5-HT[1A]Dro
  • 5-HT[[1ADro]]
  • 5-HT[[1A]]
  • 5-HT[[1A]]DRO
  • 5HT-R2A
  • 5HT-dro2A
  • 5HT-drp[[2A]]
  • 5HT1A
  • 5HT[[1ADro]]
  • 5htdro2a
  • CG16720
  • DRO2A
  • Dm5HTdro2A
  • Dmel\\CG16720
  • d5-HT1A
  • 5htr1a
  • htr1a
  • HTR1A
  • Htr1a
  • 5-Ht1a
  • Gpcr18
  • 5-HT-1A
  • 5-HT1A
  • 5HT1a
  • ADRB2RL1
  • ADRBRL1
  • G-21
  • PFMCD
  • RAT5HT1A
  • 5ht1a
  • adrb2rl1
  • adrbrl1
  • htr1a-A
  • Serotonin receptor 1A
  • 5-hydroxytryptamine (serotonin) receptor 1A
  • 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • 5-hydroxytryptamine (serotonin) receptor 1A a
  • 5-HT1A
  • HTR1A
  • htr1aa
  • Htr1a
  • htr1a
Reactivity
Mouse (Murine), Rat (Rattus)
37
31
23
1
1
Host
Rabbit
31
15
1
Clonality
Polyclonal
Conjugate
This Serotonin Receptor 1A antibody is un-conjugated
2
2
1
1
1
1
Application
Dot Blot (DB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
43
26
6
4
3
3
2
1
1
Supplier
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Catalog No. ABIN492739
$ 456.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2746131 IP ELISA WB FITC Rabbit IgG AA 200-250 Log in to see Polyclonal
1 ABIN2746130 IP ELISA WB Rabbit IgG AA 200-250 Log in to see Polyclonal
1 ABIN5558155 ELISA IP WB Biotin Rabbit Log in to see Polyclonal

Top referenced anti-Serotonin Receptor 1A antibody for Immunoprecipitation

Similar anti-Serotonin Receptor 1A Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Dot Blot (DB) 1 Antibodies 1 Antibodies
ELISA 10 Antibodies 19 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Immunoelectron Microscopy (IEM) 1 Antibodies 1 Antibodies
Immunofluorescence (IF) 3 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 3 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies 4 Antibodies
Immunoprecipitation (IP) 4 Antibodies 4 Antibodies
Western Blotting (WB) 22 Antibodies

General

Antigen Serotonin Receptor 1A (HTR1A) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(37), (31), (23), (1), (1)
Host Rabbit
(31), (15), (1)
Clonality
Polyclonal
Conjugate This Serotonin Receptor 1A antibody is un-conjugated
(2), (2), (1), (1), (1), (1)
Application Dot Blot (DB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(43), (26), (6), (4), (3), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Serotonin Receptor 1A Antibody

Target Details Serotonin Receptor 1A Application Details Handling ProductDetails: References for anti-Serotonin Receptor 1A antibody (ABIN492739) Images
Sequence RTP EDR SDP DAC TIS KDH GY
Specificity Recognizes 5HT1A
Purification Antigen Affinity Chromatography
Immunogen This antibody was generated against unique peptide selected form particular 5HT receptor isoform.

Target Details Serotonin Receptor 1A

Product Details anti-Serotonin Receptor 1A Antibody Application Details Handling ProductDetails: References for anti-Serotonin Receptor 1A antibody (ABIN492739) Images back to top
Antigen
Background The serotonergic system is involved in both pathophysiology and treatment of addiction, depression or mood disorders, appetite control, cardiovascular function, motility of GI tract and sexual function. Serotonin (5-HT) has long been implicated in a number of neurodevelopmental processes including neuronal cell division, migration, neurite outgrowth, and synapse formation which regulate and control some of the above physiological manifestations. Molecular cloning of 5HT receptors have identified a family of closely related genes that encodes several proteins with extensive splice variants exhibiting high degree of amino acid homology (45 % -65 %) all in the molecular weight range of 40-60 kDa. In brain the 5HT1A binding sites are tightly coupled to oestrous cycle and sex hormone levels (1). Serotonin receptors, also known as 5HT receptors are G-protein coupled rectors (7 transmembrane domains) that elicit the serotonin mediated effects on the above diverse physiological functions. There are at least 7 members of 5HT receptors (5HT1-5HT7), the 5HT1 is further divided in to 6 subtypes (5HT1A-5HT1F) each with multiple variants expressed as a results of alternate splicing or use of alternate initiation codons. Serotonin is reabsorbed by serotonin reuptake transporter which is coupled to sodium/calcium pump. 5HT1A receptors are grouped among the GPCR with characteristic 7TMD. There are several variants isoform of the 5HT1A receptors (5HT1A-5HT1E). The type if signal transduction could be excitatory or inhibitory depending upon the receptor functional coupling to the signal transduction complex. Certain beta arrestins are co-localized with 5HT receptors, where they act in concert with Bark1 or GRK1 and GRK 2 to regulate the expression of the GPCRs. All 5HT receptor proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. 5HT receptors are believed to be associated with other proteins including members of the dopamine receptors and opiod receptors resulting in a significant increase in their apparent molecular weight.Synonyms: 5-HT-1A, 5-HT1A, 5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1
Gene ID 3350
NCBI Accession NP_000515
UniProt P08908
Pathways JAK-STAT Signaling, Synaptic Membrane, Feeding Behaviour

Application Details

Product Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Handling ProductDetails: References for anti-Serotonin Receptor 1A antibody (ABIN492739) Images back to top
Application Notes ELISA: 1/50,000Dot Blot: 1/50,000Western Blot: 1/2,5000-1/5,000 using 100 μg protein from rat striatal membrane. IMM: 4 μL of 5HT1A receptor antibody (ABIN492739) will immunoprecipitate 65-75 % 5HT1Areceptor protein from solubilized COS1 cells transfected with 5HT1A cDNA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Application Details ProductDetails: References for anti-Serotonin Receptor 1A antibody (ABIN492739) Images back to top
Buffer Stabilized buffer with preservatives
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at-20 °C.

ProductDetails: References for anti-Serotonin Receptor 1A antibody (ABIN492739)

Product Details anti-Serotonin Receptor 1A Antibody Target Details Serotonin Receptor 1A Application Details Handling Images back to top
Background publications

Flügge, Pfender, Rudolph, Jarry, Fuchs: "5HT1A-receptor binding in the brain of cyclic and ovariectomized female rats." in: Journal of neuroendocrinology, Vol. 11, Issue 4, pp. 243-9, 1999