anti-Human STAT6 antibody for Enzyme Immunoassay

Recommended STAT6 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antibodies
  • D12S1644
  • IL-4-STAT
  • STAT6B
  • STAT6C
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6-like
  • STAT6
  • Stat6
  • LOC100859543
Reactivity
Dog (Canine), Human
441
189
133
24
19
17
15
14
9
6
3
2
1
1
1
Host
Mouse
288
178
6
2
1
Clonality
Monoclonal
Conjugate
This STAT6 antibody is un-conjugated
17
17
15
14
13
10
8
8
6
6
6
6
6
5
5
5
5
5
5
5
4
3
3
3
3
3
3
3
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
340
148
135
67
54
51
46
39
35
11
5
4
4
3
2
1
1
1
1
1
1
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Catalog No. ABIN126902
$ 555.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN126901 EIA IHC (fro) WB Mouse IgG1 pTyr641 Log in to see 1-60E-013
1 ABIN1109154 EIA IF WB Mouse IgG1 Log in to see 7D3 3
1 ABIN318132 EIA IHC (p) IP WB Rabbit pThr645 Log in to see Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antibodies
Reactivity Dog (Canine), Human
(441), (189), (133), (24), (19), (17), (15), (14), (9), (6), (3), (2), (1), (1), (1)
Host Mouse
(288), (178), (6), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT6 antibody is un-conjugated
(17), (17), (15), (14), (13), (10), (8), (8), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(340), (148), (135), (67), (54), (51), (46), (39), (35), (11), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-STAT6 Antibody

Target Details STAT6 Application Details Handling Images
Specificity This antibody specifically recognizes STAT6 at 100 kDa.
Characteristics Synonyms: STAT-6, IL-4 Stat, IL-4-STAT, Signal transducer and activator of transcription 6
Purification Size Exclusion Chromatography
Components incl. positive Control
Immunogen Synthetic peptide conjuagted to KLH
Clone 8C12
Isotype IgG1

Target Details STAT6

Product Details anti-STAT6 Antibody Application Details Handling Images back to top
Antigen
Alternative Name STAT6 (STAT6 Antibody Abstract)
Background The STAT proteins serve as both cytoplasmic signal transducers and nuclear activators of transcription. STATs are mediators involved in cytokine signalling. In response to a specific cytokine signal, STAT proteins are phosphorylated on conserved tyrosine residues. Phosphorylated STAT proteins dimerize via their SH2 domains and move to the nucleus. The STAT dimers bind to specific DNA elements resulting in transcriptional regulation of downstream target genes. STAT6 is activated primarily by IL-4 and IL-13. Upon activation, STAT6 is phosphorylated at tyrosine 641 by Janus Kinase (JAK). Phosphorylated STAT6 forms head-to-tail heterodimers and translocates to the nucleus where it paricipates in transcriptional control.Synonyms: IL-4 Stat, Signal transducer and activator of transcription 6
Gene ID 6778
UniProt P42226
Research Area Chromatin and Nuclear Signaling, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-STAT6 Antibody Target Details STAT6 Handling Images back to top
Application Notes Western Blot: 1 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.05 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-STAT6 Antibody Target Details STAT6 Application Details Images back to top
Reconstitution Restore with 1 mL H2O (15 min, RT).
Buffer 1 mL2 x PBS / 0.09 % Sodium Azide / PEG and Sucrose
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C/-80 °C
Storage Comment Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.
Expiry Date 12 months

Images

Product Details anti-STAT6 Antibody Target Details STAT6 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibody (ABIN126902) anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibody