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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Simple Western (SimWes)||3 Antibodies||2 Antibodies||2 Antibodies|
|Western Blotting (WB)||298 Antibodies||97 Antibodies||68 Antibodies|
|Intracellular Staining (ICS)||8 Antibodies||5 Antibodies||2 Antibodies|
|Immunoprecipitation (IP)||52 Antibodies||33 Antibodies||7 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||41 Antibodies||24 Antibodies||17 Antibodies|
|Immunohistochemistry (IHC)||113 Antibodies||32 Antibodies||26 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||4 Antibodies||1 Antibodies|
|Antigen||Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Antibodies|
|Epitope||AA 13-29, N-Term Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This STAT6 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-STAT6 AntibodyTarget Details STAT6 Application Details Handling Images
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Signal transducer and activator of transcription 6(STAT6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: signal transducer and activator of transcription 6, interleukin-4 induced
Protein Name: Signal transducer and activator of transcription 6
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the N-terminus of human STAT6(13-29aa EKVQRLYVDFPQHLRHL), different from the related rat sequence by one amino acid, and from the mouse sequence by two amino acids.|
Target Details STAT6Product Details anti-STAT6 Antibody Application Details Handling Images back to top
|Alternative Name||STAT6 (STAT6 Antibody Abstract)|
|Background||STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors. The gene spans 19 kb and contains 23 exons. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2(Th2), expression of cell surface markers, and class switch of immunoglobulins.|
|Research Area||Chromatin and Nuclear Signaling, Signaling, Receptors, Inflammation|
Application DetailsProduct Details anti-STAT6 Antibody Target Details STAT6 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
|Restrictions||For Research Use only|
HandlingProduct Details anti-STAT6 Antibody Target Details STAT6 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Thimerosal (Merthiolate),Sodium azide a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
|Expiry Date||12 months|
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