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Browse our PEX14 Proteins (PEX14)

Full name:
Peroxisomal Biogenesis Factor 14 Proteins (PEX14)
On are 8 Peroxisomal Biogenesis Factor 14 (PEX14) Proteins from 4 different suppliers available. Additionally we are shipping PEX14 Antibodies (70) and many more products for this protein. A total of 83 PEX14 products are currently listed.
ATPEX14, dJ734G22.2, MQB2.13, MQB2_13, NAPP2, PBD13A, PED2, peroxin 14, PEROXISOME DEFECTIVE 2, Pex14p, R75137
list all proteins Gene Name GeneID UniProt
PEX14 5195 O75381
PEX14 56273 Q9R0A0
Rat PEX14 PEX14 64460 Q642G4

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PEX14 Proteins (PEX14) by Origin

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More Proteins for PEX14 Interaction Partners

Arabidopsis thaliana Peroxisomal Biogenesis Factor 14 (PEX14) interaction partners

  1. PEX5 (show PEX5 Proteins) binding to the PEX14N-terminal domain (PEX14N) has no effect on the affinity of PEX5 (show PEX5 Proteins) for a PTS1 containing peptides.

  2. PEX14 facilitates peroxisomal matrix protein import in plants.

Human Peroxisomal Biogenesis Factor 14 (PEX14) interaction partners

  1. data reveal subpopulations of peroxisomes showing only weak colocalization between PEX14 and PEX5 (show PEX5 Proteins) or PEX11 but at the same time a clear compartmentalized organization. This compartmentalization, which was less evident in cases of strong colocalization, indicates dynamic protein reorganization linked to changes occurring in the peroxisomes.

  2. PEX14 is the 13th PEX (show PHEX Proteins) gene responsible for peroxisome biogenesis disorders. Thus far, only two patients with PEX14 deficiency have been reported.

  3. The novel Pex14-binding site may represent the initial tethering site of Pex5 (show PEX5 Proteins) from which the cargo-loaded receptor is further processed in a sequential manner.

  4. interaction of PEX5 (show PEX5 Proteins) with catalase (show CAT Proteins) and PEX14

  5. PEX14 is a multi-tasking protein that not only facilitates peroxisomal protein (show FNDC5 Proteins) import but is also required for peroxisome motility by serving as membrane anchor for microtubules.

  6. peroxisomal localization of Pex14p is affected by Pex13p (show PEX13 Proteins)

  7. a new complementation group of the peroxisome biogenesis disorders with PEX14 as the defective gene

  8. This report represents the second PEX14-deficiency associated with Zellweger syndrome (show PEX1 Proteins) and the first documentation of a PEX14-deficient patient with detailed clinical follow-up and biochemical, morphological, and radiological data.

  9. N-terminal domain of Pex14, Pex14(N), adopts a three-helical fold. Pex5 (show PEX5 Proteins) and Pex19 (show PEX19 Proteins) ligand helices bind competitively to the same surface in Pex14(N) albeit with opposite directionality.

  10. analysis of the human Pex5 (show PEX5 Proteins).Pex14.PTS1 protein complex structure obtained by small angle X-ray scattering

PEX14 Protein Profile

Protein Summary

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

Alternative names and synonyms associated with PEX14

  • peroxisomal biogenesis factor 14 (PEX14)
  • peroxin 14 (PEX14)
  • peroxisomal biogenesis factor 14 (Pex14)
  • ATPEX14 protein
  • dJ734G22.2 protein
  • MQB2.13 protein
  • MQB2_13 protein
  • NAPP2 protein
  • PBD13A protein
  • PED2 protein
  • peroxin 14 protein
  • Pex14p protein
  • R75137 protein

Protein level used designations for PEX14

peroxisomal membrane protein PEX14 , NF-E2 associated polypeptide 2 , PTS1 receptor docking protein , PTS1 receptor-docking protein , peroxin-14 , peroxisomal membrane anchor protein PEX14 , peroxisomal membrane anchor protein Pex14p , peroxisomal protein Pex14

507393 Bos taurus
836402 Arabidopsis thaliana
5195 Homo sapiens
56273 Mus musculus
64460 Rattus norvegicus
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