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anti-Human ERK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ERK2 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 1 (MAPK1) Antibodies
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • ATMPK2
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • T30E16.13
  • T30E16_13
  • mitogen-activated protein kinase homolog 2
  • ERK2
  • zERK2
  • MAPK1
  • ERK
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • erk
  • erk2
  • ert1
  • mapk
  • mpk1
  • xp42
  • mapk2
  • prkm1
  • prkm2
  • Xp42
  • mapk1b
  • mapk1
  • mapk1a
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 2
  • mitogen activated protein kinase 1
  • ATMPK1
  • MPK1
  • MPK2
  • MAPK1
  • mapk1
  • Mapk1
  • PfMAP1
  • PVX_084965
  • Tsp_01601
  • mapk1-b
  • mapk1-a
Epitope
C-Term
61
25
15
9
8
8
7
7
5
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
326
107
71
36
17
7
5
3
3
2
2
2
1
1
1
1
Host
Rabbit
165
160
18
3
2
Clonality
Polyclonal
Conjugate
This ERK2 antibody is un-conjugated
8
8
7
7
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
301
145
91
82
69
52
51
26
19
9
5
3
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN359631
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.229836 ABIN359461 EIA IHC (p) WB Rabbit Ig Middle Region Log in to see Polyclonal 5
11.229836 ABIN258758 ICC IHC (fro) IF IHC (p) IHC ELISA WB Mouse IgG2a Log in to see 4C11
11.229836 ABIN438932 ICC IF IHC IHC (p) IP PLA WB Rabbit AA 310-360 Log in to see Polyclonal
11.229836 ABIN4309411 IHC IHC (p) IP WB Mouse IgG1 Transcript Variant 2 Log in to see 6E5
11.229836 ABIN305764 IHC (fro) IHC (p) ELISA WB Mouse IgG2a Log in to see 4C11C11C4
11.229836 ABIN4309425 IHC IHC (p) Rabbit C-Term Log in to see Polyclonal
11.229836 ABIN4309410 ELISA FACS IHC (p) WB Mouse IgG2b Log in to see 3F8
1 ABIN391367 FACS IHC (p) WB Rabbit Ig AA 154-183, Center Log in to see Polyclonal 3
1 ABIN391720 IHC (p) WB Rabbit Ig AA 254-285, C-Term Log in to see Polyclonal 2
1 ABIN1882175 FACS IHC (p) WB Rabbit AA 316-345, C-Term Log in to see Polyclonal 5
1 ABIN1107133 IF IHC (p) WB Mouse IgG2a Log in to see 4C11 2
1 ABIN302975 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN400733 EIA IHC (fro) IHC (p) WB Mouse IgG2a Log in to see 4C11C11C4
1 ABIN1687923 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1687922 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1499292 IHC (p) WB Mouse IgG1 Log in to see 6E5
1 ABIN1499293 IHC (p) WB Mouse IgG2a Log in to see 9H1
1 ABIN1499291 IHC (p) IP WB Mouse IgG1 Log in to see 9E9
1 ABIN1499289 IF IHC (p) IP WB Mouse IgG1 Log in to see 4C2
1 ABIN373411 IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Top referenced anti-ERK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-ERK2 Antibodies

Application / Reactivity Human
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Chromatin Immunoprecipitation (ChIP) 1 Antibodies
Dot Blot (DB) 1 Antibodies
Electron Microscopy (EM) 1 Antibodies
ELISA 137 Antibodies
Enzyme Immunoassay (EIA) 10 Antibodies
Flow Cytometry (FACS) 19 Antibodies
Immunoassay (IA) 1 Antibodies
Immunocytochemistry (ICC) 51 Antibodies
Immunofluorescence (IF) 82 Antibodies
Immunohistochemistry (IHC) 83 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 26 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 67 Antibodies
Immunoprecipitation (IP) 40 Antibodies
Immunostaining (ISt) 1 Antibodies
Intracellular Staining (ICS) 3 Antibodies
Luminex Assay (LMNX) 5 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies

General

Antigen Mitogen-Activated Protein Kinase 1 (MAPK1) Antibodies
Epitope C-Term
(61), (25), (15), (9), (8), (8), (7), (7), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(326), (107), (71), (36), (17), (7), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(165), (160), (18), (3), (2)
Clonality
Polyclonal
Conjugate This ERK2 antibody is un-conjugated
(8), (8), (7), (7), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(301), (145), (91), (82), (69), (52), (51), (26), (19), (9), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-ERK2 Antibody

Target Details ERK2 Application Details Handling References for anti-ERK2 Antibody (ABIN359631) Images
Specificity This antiobdy reacts to ERK2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ERK2.
Isotype Ig

Target Details ERK2

Product Details anti-ERK2 Antibody Application Details Handling References for anti-ERK2 Antibody (ABIN359631) Images back to top
Antigen
Alternative Name ERK2 (MAPK1 Antibody Abstract)
Background ERK2 is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.Synonyms: ERT1, Extracellular signal-regulated kinase 2, MAP kinase 2, MAPK1, MAPK2, Mitogen-activated protein kinase 1, PRKM1, PRKM2, p42-MAPK
Gene ID 5594, 9606
UniProt P28482
Research Area Stem Cells, Signaling, Inflammation
Pathways MAPK Signaling, RTK Signaling, Apoptosis, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-ERK2 Antibody Target Details ERK2 Handling References for anti-ERK2 Antibody (ABIN359631) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ERK2 Antibody Target Details ERK2 Application Details References for anti-ERK2 Antibody (ABIN359631) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-ERK2 Antibody (ABIN359631)

Product Details anti-ERK2 Antibody Target Details ERK2 Application Details Handling Images back to top
Background publications

Grey, Chen, Xu, Callon, Cornish et al.: "Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic ..." in: Endocrinology, Vol. 144, Issue 11, pp. 4886-93, 2003

Lin, Chuang, Yang: "Persistent activation of ERK1/2 by lead acetate increases nucleotide excision repair synthesis and confers anti-cytotoxicity and anti-mutagenicity." in: Carcinogenesis, Vol. 24, Issue 1, pp. 53-61, 2003

Liao, Hung: "Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis." in: Molecular and cellular biology, Vol. 23, Issue 19, pp. 6836-48, 2003

García-Lora, Martinez, Pedrinaci, Garrido: "Different regulation of PKC isoenzymes and MAPK by PSK and IL-2 in the proliferative and cytotoxic activities of the NKL human natural killer cell line." in: Cancer immunology, immunotherapy : CII, Vol. 52, Issue 1, pp. 59-64, 2003

Sawafuji, Miyakawa, Kizaki, Ikeda: "Cyclosporin A induces erythroid differentiation of K562 cells through p38 MAPK and ERK pathways." in: American journal of hematology, Vol. 72, Issue 1, pp. 67-9, 2002

Images

Product Details anti-ERK2 Antibody Target Details ERK2 Application Details Handling References for anti-ERK2 Antibody (ABIN359631) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ERK2 antibody (Mitogen-Activated Protein Kinase 1) (C-Term) (ABIN359631) Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ERK2 ...
Western Blotting (WB) image for anti-ERK2 antibody (Mitogen-Activated Protein Kinase 1) (C-Term) (ABIN359631) Western blot analysis of anti-ERK2 C-term Pab in UV-treated HL-60 cell lysate. ERK2 (...