anti-Human JNK antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended JNK Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 8 (MAPK8) Antibodies
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • c-Jun
  • dJNK
  • jnk
  • JNK-46
  • JNK1
  • JNK1A2
  • JNK21B1/2
  • PRKM8
  • SAPK1
  • SAPK1c
  • AI849689
  • Prkm8
  • jnk1
  • sapk1
  • T10F20.15
  • mapk8
  • zgc:112379
  • basket
  • mitogen-activated protein kinase 8
  • mitogen-activated protein kinase 8b
  • Protein JNK-1
  • bsk
  • MAPK8
  • Mapk8
  • mapk8
  • ATMPK8
  • mapk8b
  • jnk-1
Epitope
AA 162-199
110
64
29
17
15
15
14
13
10
10
10
10
10
9
8
7
7
7
6
5
5
5
5
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
419
200
169
23
19
13
8
8
6
4
3
3
3
2
2
2
2
1
1
Host
Rabbit
318
116
3
2
Clonality
Polyclonal
Conjugate
This JNK antibody is un-conjugated
21
19
15
13
11
11
5
4
3
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
333
210
100
75
62
62
39
37
31
22
18
8
4
3
3
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN953314
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.671394 ABIN4327964 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 1
13.671394 ABIN462091 IHC (p) WB Rabbit N-Term Log in to see Polyclonal
13.671394 ABIN498747 IF IHC (p) WB Rabbit pThr183 Log in to see Polyclonal
13.671394 ABIN498285 IF IHC (p) WB Rabbit Log in to see Polyclonal
13.671394 ABIN498628 IHC (p) WB Rabbit Log in to see Polyclonal
13.671394 ABIN498627 IF IHC (p) WB Rabbit Log in to see Polyclonal
13.671394 ABIN4327962 ICC IF IHC IHC (p) WB Mouse IgG2a Log in to see 4E3
1 ABIN654887 IHC (p) WB Rabbit Ig AA 159-195, Thr183, Tyr185 Log in to see Polyclonal 3
1 ABIN391724 IF IHC (p) WB Rabbit Ig AA 358-389, C-Term Log in to see Polyclonal 6
1 ABIN4327961 IHC IHC (p) WB Rabbit pThr183 Log in to see Polyclonal 2
1 ABIN747713 IF (p) IHC (p) WB Rabbit IgG AA 160-210 Log in to see Polyclonal 1
1 ABIN732368 IF (p) IHC (p) WB Rabbit IgG AA 170-210, pThr183, pTyr185 Log in to see Polyclonal 11
1 ABIN3042709 ICC IHC (p) WB Rabbit IgG AA 344-363, Middle Region Log in to see Polyclonal
1 ABIN2854959 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN953306 EIA IHC (p) IP WB Mouse IgG2a Log in to see 2F3
1 ABIN953307 EIA IHC (p) IP WB Mouse IgG2a Log in to see 3H2
1 ABIN127312 IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
1 ABIN2878886 IF IHC (p) ELISA WB Rabbit IgG AA 166-215 Log in to see Polyclonal
1 ABIN1490768 ICC IF IHC (p) WB Mouse IgG1 AA 1-384 Log in to see 2C6
1 ABIN953308 EIA IHC (p) WB Mouse IgG2a Log in to see 1-00E-001

General

Antigen Mitogen-Activated Protein Kinase 8 (MAPK8) Antibodies
Epitope AA 162-199
(110), (64), (29), (17), (15), (15), (14), (13), (10), (10), (10), (10), (10), (9), (8), (7), (7), (7), (6), (5), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(419), (200), (169), (23), (19), (13), (8), (8), (6), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(318), (116), (3), (2)
Clonality
Polyclonal
Conjugate This JNK antibody is un-conjugated
(21), (19), (15), (13), (11), (11), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(333), (210), (100), (75), (62), (62), (39), (37), (31), (22), (18), (8), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-JNK Antibody

Target Details JNK Application Details Handling References for anti-JNK antibody (ABIN953314) Images
Specificity This antibody recognizes Human and Mouse MAPK8 / JNK1 (Thr183/Tyr185).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 162-199 amino acids from human MAPK8 / JNK1
Isotype Ig

Target Details JNK

Product Details anti-JNK Antibody Application Details Handling References for anti-JNK antibody (ABIN953314) Images back to top
Antigen
Alternative Name MAPK8 / JNK1 (MAPK8 Antibody Abstract)
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.Synonyms: JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
Molecular Weight 48296 Da
Gene ID 5599
NCBI Accession NP_002741
Pathways MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-JNK Antibody Target Details JNK Handling References for anti-JNK antibody (ABIN953314) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-JNK Antibody Target Details JNK Application Details References for anti-JNK antibody (ABIN953314) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-JNK antibody (ABIN953314)

Product Details anti-JNK Antibody Target Details JNK Application Details Handling Images back to top
Background publications

Dasgupta, Kar, Liu, Joseph, Kalyanaraman, Remington, Chen, Melendez: "Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase." in: Journal of cellular physiology, Vol. 225, Issue 1, pp. 52-62, 2010

Gao, Nong, Huang, Lu, Zhao, Lin, Man, Wang, Yang, Li: "The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 29965-73, 2010

Han, Crowe: "Jun amino-terminal kinase 1 activation promotes cell survival in ErbB2-positive breast cancer." in: Anticancer research, Vol. 30, Issue 9, pp. 3407-12, 2010

Yang, Zheng, Cao, Xiang, Liu, Lv: "8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK." in: World journal of gastroenterology : WJG, Vol. 16, Issue 27, pp. 3385-93, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Images

Product Details anti-JNK Antibody Target Details JNK Application Details Handling References for anti-JNK antibody (ABIN953314) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 162-199) antibody (ABIN953314) Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tis...
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 162-199) antibody (ABIN953314) Western blot analysis of MAPK8 / JNK1 Antibody (Thr183/Tyr185) in mouse liver tissue ...