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anti-Rat (Rattus) JNK antibody for Flow Cytometry

Recommended JNK Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase 8 (MAPK8) Antibodies
  • AI849689
  • Bsk
  • BSK
  • BSK/DJNK
  • c-Jun
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • dJNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • jnk
  • JNK
  • Jnk
  • JNK-46
  • JNK/SAPK
  • JNK1
  • jnk1
  • JNK1A2
  • JNK21B1/2
  • Junk
  • mapk8
  • Prkm8
  • PRKM8
  • sapk1
  • SAPK1
  • SAPK1c
  • SAPKa
  • T10F20.15
  • zgc:112379
Epitope
pThr183
95
58
33
22
18
15
15
15
13
13
13
10
10
10
10
5
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
374
132
112
17
15
7
6
4
2
2
2
1
1
Host
Mouse
307
93
2
Clonality
Monoclonal
Conjugate
This JNK antibody is un-conjugated
18
16
14
11
11
10
4
3
3
3
3
3
3
3
3
Application
Flow Cytometry (FACS), Western Blotting (WB)
299
195
92
65
53
53
39
33
17
15
9
6
4
3
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN968866
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010482287 ABIN968867 FACS WB Mouse IgG1 pThr183 Log in to see 41-JNK-SAPK 5
0.0010482287 ABIN2665469 FACS Rabbit Log in to see Polyclonal 3
0.0010482287 ABIN4327963 ELISA FACS WB Mouse IgG1 Log in to see 1-00E05
0.0010482287 ABIN2665470 FACS Rabbit Log in to see Polyclonal

Top referenced anti-JNK antibody for Flow Cytometry

Similar anti-JNK Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 280 Antibodies 92 Antibodies 76 Antibodies
RNA Interference (RNAi) 1 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies
Intracellular Staining (ICS) 2 Antibodies 2 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 47 Antibodies 5 Antibodies 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 65 Antibodies 23 Antibodies 20 Antibodies
Immunohistochemistry (IHC) 91 Antibodies 32 Antibodies 28 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies 4 Antibodies 3 Antibodies

General

Antigen Mitogen-Activated Protein Kinase 8 (MAPK8) Antibodies
Epitope pThr183
(95), (58), (33), (22), (18), (15), (15), (15), (13), (13), (13), (10), (10), (10), (10), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(374), (132), (112), (17), (15), (7), (6), (4), (2), (2), (2), (1), (1)
Host Mouse
(307), (93), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This JNK antibody is un-conjugated
(18), (16), (14), (11), (11), (10), (4), (3), (3), (3), (3), (3), (3), (3), (3)
Application Flow Cytometry (FACS), Western Blotting (WB)
(299), (195), (92), (65), (53), (53), (39), (33), (17), (15), (9), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-JNK Antibody

Target Details JNK Application Details Handling References for anti-JNK Antibody (ABIN968866) Images
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Phosphorylated Human JNK/SAPK (pT183/pY185) Peptide
Clone 41-JNK-SAPK
Isotype IgG1

Target Details JNK

Product Details anti-JNK Antibody Application Details Handling References for anti-JNK Antibody (ABIN968866) Images back to top
Antigen
Alternative Name JNK (MAPK8 Antibody Abstract)
Background The Ras signaling pathway links the signals from growth factor receptors with the activation of the MAPK kinase cascade of phosphorylation leading to cell growth and differentiation. External stimuli, like endotoxins, UV irradiation, heat, and hyperosmolarity, induce an array of cellular responses that culminate with gene expression, ultimately dictating an adaptation to the new environment. Small GTPases of the Rho family, including cdc42, Rac1, and Rho, transmit the stress signals that initiate the signal cascade. JNK is a c-Jun kinase that was also identified as SAPK1 and MAPKp49. JNK/SAPK, along with p38 and RK5/BMK1, comprise three classes of stress-activated MAPK groups. Complete activation of JNK/SAPK requires the phosphorylation of both Thr183 and Tyr185, which are located in a Thr-X-Tyr motif. The activation of these residues is believed to be carried out by MKK4 and MKK7. Active JNK/SAPK phosphorylates other kinases and multiple transcription factors that induce expression of genes, such as proinflammatory cytokines.
Molecular Weight 43 & 56 kDa
Pathways MAPK Signaling, WNT Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-JNK Antibody Target Details JNK Handling References for anti-JNK Antibody (ABIN968866) Images back to top
Comment

Related Products: ABIN968535, ABIN968632, ABIN967389, ABIN968074

Restrictions For Research Use only

Handling

Product Details anti-JNK Antibody Target Details JNK Application Details References for anti-JNK Antibody (ABIN968866) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

References for anti-JNK Antibody (ABIN968866)

Product Details anti-JNK Antibody Target Details JNK Application Details Handling Images back to top
Product cited in:

Fleming, Armstrong, Morrice, Paterson, Goedert, Cohen: "Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7." in: The Biochemical journal, Vol. 352 Pt 1, Issue 3, pp. 145-54, 2001

Kyriakis, Avruch: "Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation." in: Physiological reviews, Vol. 81, Issue 2, pp. 807-69, 2001

Muyembe, Maes, Makulu, Ghysels, Vandeven, Vandepitte: "The hem of the garment." in: Seminars in dialysis, Vol. 14, Issue 1, pp. 76, 2001

Hinton, Henderson, Blanks, Rudnicka, Miller: "Monoclonal antibodies react with neuronal subpopulations in the human nervous system." in: The Journal of comparative neurology, Vol. 267, Issue 3, pp. 398-408, 1988

Images

Product Details anti-JNK Antibody Target Details JNK Application Details Handling References for anti-JNK Antibody (ABIN968866) back to top
Supplier Images
Western Blotting (WB) image for anti-JNK antibody (Mitogen-Activated Protein Kinase 8) (pThr183) (ABIN968866) Western blot analysis for JNK/SAPK (pT183/pY185). HeLa cells (Human cervical epithelo...