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Rat (Rattus) MAPK3 ELISA Kit for Sandwich ELISA - ABIN432074
Du, Wang, Wang: Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome. in Graefe's archive for clinical and experimental ophthalmology 2016
Data report that MPK3/MPK6 and their substrate ERF6 promote the biosynthesis of IGSs and the conversion of I3G to 4MI3G, a target of PEN2/PEN3-dependent chemical defenses in plant immunity.
Data show that the protein kinases MPK3 and MPK6 (show MAPK6 ELISA Kits) can both interact with SPOROCYTELESS/NOZZLE (SPL (show SGPL1 ELISA Kits)) in vitro and in vivo and can phosphorylate the SPL (show SGPL1 ELISA Kits) protein in vitro.
MKK4 (show MAP2K4 ELISA Kits), MKK5 (show MAP2K5 ELISA Kits), MKK7 (show MAP2K7 ELISA Kits), and MKK9, are responsible for the activation of MPK3 and MPK6 (show MAPK6 ELISA Kits) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (show MAPK1 ELISA Kits) signaling through MKK4 (show MAP2K4 ELISA Kits)/5/7/9-MPK3/6 cascades.
Phosphatase AP2C1, as well as AP2C1-targeted MPK3 and MPK6 (show MAPK6 ELISA Kits), are important regulators of plant-nematode interaction, where the co-ordinated action of these signalling components ensures the timely activation of plant defence.
Results demonstrated the contribution of MPK3 and MPK6 (show MAPK6 ELISA Kits) to riboflavin-induced resistance.
These results indicate that the MVB pathway is positively regulated by pathogen-responsive MPK3/6 through LIP5 phosphorylation and plays a critical role in plant immune system
MKK3-MPK6 is activated by blue light in a MYC2-dependent manner.
MPK3 and MPK6 (show MAPK6 ELISA Kits) target a subclass of 'VQ-motif'-containing proteins to regulate immune responses.
MicroRNA biogenesis factor DRB1 (show EPHX1 ELISA Kits) is a phosphorylation target of mitogen activated protein kinase (show MAPK1 ELISA Kits) MPK3 in both rice and Arabidopsis
MPK3 represses the constitutive and flg22-induced expression of defence genes in Arabidopsis thaliana.
MAPK3/1 is involved in luteinizing hormone-mediated decrease of C-type natriuretic peptide (show NPPC ELISA Kits) and this process is related to the EGFR (show EGFR ELISA Kits) and MAPK3/1 signal pathways
Chronic hypoxia induces Egr-1 (show EGR1 ELISA Kits) via activation of ERK1/2 (show MAPK1/3 ELISA Kits) and contributes to pulmonary vascular remodeling.
ER Ca(2 (show CA2 ELISA Kits)+) release enhances eNOS (show NOS3 ELISA Kits) Ser (show SIGLEC1 ELISA Kits)-635 phosphorylation and function via ERK1/2 (show MAPK1/3 ELISA Kits) activation.
Thrombospondin 1 (show THBS1 ELISA Kits), fibronectin (show FN1 ELISA Kits), and vitronectin (show VTN ELISA Kits) are differentially dependent upon RAS, ERK1/2 (show MAPK1/3 ELISA Kits), and p38 (show MAPK14 ELISA Kits) for induction of vascular smooth muscle cell chemotaxis.
results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation
These data suggest that Gab1-ERK1/2 (show MAPK1/3 ELISA Kits) binding and their nuclear translocation play a crucial role in Egr-1 (show EGR1 ELISA Kits) nuclear accumulation.
data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 ELISA Kits), mTOR (show FRAP1 ELISA Kits), p70S6K (show RPS6KB1 ELISA Kits), and ERK1/2 (show MAPK1/3 ELISA Kits).
This study demonstrates for the first time that cyclic mechanical stretch induces the proliferation of bovine satellite cells and suppresses their myogenic differentiation through the activation of ERK (show MAPK1 ELISA Kits).
findings indicate that exposure to DHEA, at concentrations found in human blood, causes vascular endothelial proliferation by a plasma membrane-initiated activity that is Gi/o and ERK1/2 (show MAPK1/3 ELISA Kits) dependent.
Results suggest that estrogen receptors and the ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathway are involved in the anti-apoptotic action of LY117018 in vascular endothelial cells.
The results suggest that the MPK-1 (show MAPK1 ELISA Kits)/ERK (show MAPK1 ELISA Kits) regulatory network, including FBF-1 (show FBF1 ELISA Kits), FBF-2, and LIP-1 (show CENPJ ELISA Kits), controls the number of sperm by regulating the timing of the sperm-oocyte switch in C. elegans.
Cek2 (show FGFR3 ELISA Kits) has a cryptic role in cell-wall biogenesis and its role is not entirely redundant to Cek1.
knockdown of SUV420H1 (show SUV420H1 ELISA Kits) reduced phosphorylated ERK1 and total ERK1 proteins, and interestingly suppressed ERK1 at the transcriptional level
Secreted aspartic protease-mediated proteolytic cleavage of Msb2 is required for activation of the Cek1 mitogen activated protein kinase (show MAPK1 ELISA Kits) pathway in response to environmental cues.
The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.
Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 (show CDC42 ELISA Kits) GTPase (show RACGAP1 ELISA Kits).
ERK1/2 (show MAPK1/3 ELISA Kits)-Akt1 (show AKT1 ELISA Kits) crosstalk regulates arteriogenesis in mice and zebrafish.
eena (show SH3GL1 ELISA Kits) plays an important role in the development of the myeloid cell through activation of the ERK1/ERK2 (show MAPK1 ELISA Kits) pathway
ERK1 and ERK2 (show MAPK1 ELISA Kits) target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK1 different specific genes involved in dorsal-ventral patterning and subsequent embryonic cell migration were identified.
These results demonstrate that induction of Hsp70 (show HSPA1A ELISA Kits) in response to heat stress is dependent on ERK (show MAPK1 ELISA Kits) activation in Pac2 (show PSMG2 ELISA Kits) cells.
Data define distinct roles for ERK1 and ERK2 (show MAPK1 ELISA Kits) in developmental cell migration processes during zebrafish embryogenesis.
GLUL (show GLUL ELISA Kits) knockdown markedly inhibited the p38 MAPK (show MAPK14 ELISA Kits) and ERK1/ERK2 (show MAPK1 ELISA Kits) signaling pathways in cultured breast cancer cells and reduces their proliferation.
These results suggested that HOXB7 (show HOXB7 ELISA Kits) stimulates ERK1/2 (show MAPK1/3 ELISA Kits) phosphorylation and provided evidence that HOXB7 (show HOXB7 ELISA Kits), besides its role in transcriptional regulation, also promotes cell motility and invasiveness.
High ERK1 expression is associated with castration-resistant prostate cancer.
combined use of butyrate and highly specific Syk (show SYK ELISA Kits) inhibitor BAY61-3606 does not enhance differentiation and apoptosis of colonocytes. Instead, BAY completely abolishes butyrate-induced differentiation and apoptosis in a Syk (show SYK ELISA Kits)- and ERK1/2 (show MAPK1/3 ELISA Kits)-dependent manner.
new findings indicating that canonical FGFR (show FGFR2 ELISA Kits)-ERK1/2 (show MAPK1/3 ELISA Kits) signaling entrapped hBMSCs in a pre-committed state and arrested further maturation of committed precursors.
mutually exclusive transcriptional regulation by AP-1 (cjun (show JUN ELISA Kits)/cfos) and non-canonical NF-kappaB (show NFKB1 ELISA Kits) (RelB (show RELB ELISA Kits)/p52 (show FKBP4 ELISA Kits)) downstream of MEK (show MAP2K1 ELISA Kits)-ERK (show EPHB2 ELISA Kits) and NIK (show MAP3K14 ELISA Kits)-IKK-alpha (show CHUK ELISA Kits)-NF-kappaB2 (p100 (show CUX1 ELISA Kits)) phosphorylation, respectively was responsible for persistent Ccl20 (show CCL20 ELISA Kits) expression in the colonic cells.
LPS (show IRF6 ELISA Kits)-activated ERK1,2 was at least partly involved in the observed effects on periodontal ligament stem cell differentiation capacity, acquisition of myofibroblastic attributes, and changes of their immunomodulatory features.
The findings indicate that ERK (show EPHB2 ELISA Kits) and JNK (show MAPK8 ELISA Kits) signaling pathways, as well as NF-kappaB (show NFKB1 ELISA Kits)-mediated signaling are important contributors to the pathogenesis of Kashin-Beck disease.
The antitumor activity of scopoletin may be due to its strong anti-angiogenic effect, which may be mediated by its effective inhibition of ERK1, VEGF-A (show VEGFA ELISA Kits), and FGF-2 (show FGF2 ELISA Kits).
High ERK1 expression is associated with melanoma.
Cortical neuron-specific deletion of extracellular signal-regulated kinases Erk1 or Erk2 (show MAPK1 ELISA Kits) significantly increased the duration of wakefulness.
pERK1/2 is a regulator of CD44 (show CD44 ELISA Kits) expression, and increased CD44 (show CD44 ELISA Kits) expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
mmLDL increased the serum concentrations and expression of ICAM-1 (show ICAM1 ELISA Kits) and VCAM-1 (show VCAM1 ELISA Kits) by activating the ERK1/2 (show MAPK1/3 ELISA Kits) pathway, resulting in the expression of ETB (show EDNRB ELISA Kits) receptors and the enhancement of contractile function in vascular smooth muscle.
Angiotensin II regulates dendritic cells through activation of p65 NF-kappaB (show NFkBP65 ELISA Kits), ERK1, ERK2 (show MAPK1 ELISA Kits) and STAT1 (show STAT1 ELISA Kits) pathways.
MAPK3/1 participates in primordial follicle activation through mTORC1-KITL (show KITLG ELISA Kits) signaling.
At low oxLDL levels LOX-1 (show OLR1 ELISA Kits) activates the protective Oct-1 (show POU2F1 ELISA Kits)/SIRT1 (show SIRT1 ELISA Kits) pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 (show MAPK1/3 ELISA Kits) pathway.
Studies indicate that progesterone receptor (show PGR ELISA Kits) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (show CXCL9 ELISA Kits)-6over) phosphatase and tensin homolog protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (show MAPK1/3 ELISA Kits) and its target genes.
Gpr182 reduction led to increased activation of ERK1/2 in basal and challenge models, demonstrating a potential role for this orphan GPCR in regulating the proliferative capacity of the intestine.
ERK1 underexpression is associated with obesity.
retinoschisin (show RS1 ELISA Kits) is a novel regulator of MAP kinase (show MAPK1 ELISA Kits) signalling and exerts an anti-apoptotic effect on retinal cells.
Early activation of MAPK p44/42 is involved in deoxynivalenol -induced disruption of intestinal barrier function and tight junction network signaling.
Pseudorabies virus glycoprotein gE-mediated ERK 1/2 phosphorylation also occurs in epithelial cells and in these cells, gE-mediated ERK 1/2 signaling is associated with degradation of the pro-apoptotic protein Bim (show BCL2L11 ELISA Kits).
Treatment with ERK (show MAPK1 ELISA Kits) inhibitors or ERK1/2 (show MAPK1/3 ELISA Kits) knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.
This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 (show MAPK1/3 ELISA Kits) signaling, has a substantial impact on T cell behavior.
CSF2 (show CSF2 ELISA Kits) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 (show MAPK1/3 ELISA Kits) MAPK (show MAPK1 ELISA Kits)-dependent MTOR (show FRAP1 ELISA Kits) signal transduction cascades.
PGRN (show GRN ELISA Kits) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 ELISA Kits) activation mediated PPARgamma (show PPARG ELISA Kits) phosphorylation.
Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 ELISA Kits)/ERK (show MAPK1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis
Data show that proinflammatory cytokines induction was ERK1/2 (show MAPK1/3 ELISA Kits) and JNK1 (show MAPK8 ELISA Kits)/2 dependent.
Saccharomyces cerevisiae inhibits the Enterotoxigenic Escherichia coli-induced expression of pro-inflammatory transcripts and this inhibition was associated to a decrease of ERK1/2 (show MAPK1/3 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) phosphorylation
ERK1 phosphorylation in response to Insulin-like Growth Factor-1 (show IGF1 ELISA Kits) does not require activation of the Insulin-like Growth Factor-1 receptor tyrosine kinase (show IGF1R ELISA Kits)
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
extracellular signal-regulated kinase 1
, likely protein kinase
, MAP kinase isoform p44
, MAPK 1
, extracellular signal-related kinase 1
, insulin-stimulated MAP2 kinase
, microtubule-associated protein 2 kinase
, MAP kinase 3
, p44 MAP kinase
, pp42/MAP kinase
, MAP kinase 1
, MAPK 3
, mitogen-activated 3
, mitogen-activated protein kinase 1
, mitogen-activated protein kinase 3
, extracellular signal-regulated kinase-1