anti-Human MAPKAP Kinase 5 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MAPKAP Kinase 5 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Antibodies
  • MAPKAPK5
  • MK5
  • PRAK
  • MAPKAP-K5
  • MK-5
  • mitogen-activated protein kinase-activated protein kinase 5
  • MAP kinase-activated protein kinase 5
  • MAPKAPK5
  • mapkapk5
  • Mapkapk5
Epitope
AA 160-210, pThr182
24
20
20
14
13
10
9
6
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
159
79
15
8
7
7
3
3
3
3
3
2
2
Host
Rabbit
104
47
24
Clonality
Polyclonal
Conjugate
This MAPKAP Kinase 5 antibody is un-conjugated
7
7
7
6
6
6
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
150
87
40
22
13
13
10
4
3
1
1
1
Options
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Catalog No. ABIN710546
$ 317.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN754378 IF (p) IHC (p) WB Rabbit IgG AA 100-150 Log in to see Polyclonal
1 ABIN877597 IF (p) Alexa Fluor 350 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN877596 IF (p) Alexa Fluor 488 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN877600 IF (p) Alexa Fluor 555 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN2804002 IF (p) Alexa Fluor 594 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN877599 IF (p) Alexa Fluor 647 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN710549 IF (p) Cy3 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN710550 IF (p) Cy5 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN710551 IF (p) Cy5.5 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN710552 IF (p) Cy7 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN710553 IF (p) FITC Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN5006545 IF (p) Alexa Fluor 680 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal
1 ABIN5006546 IF (p) Alexa Fluor 750 Rabbit IgG AA 160-210, pThr182 Log in to see Polyclonal

Similar anti-MAPKAP Kinase 5 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 45 Antibodies 71 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 3 Antibodies
Immunofluorescence (IF) 3 Antibodies 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 14 Antibodies 14 Antibodies
Immunohistochemistry (IHC) 20 Antibodies 40 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Western Blotting (WB) 59 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies

General

Antigen Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Antibodies
Epitope AA 160-210, pThr182
(24), (20), (20), (14), (13), (10), (9), (6), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(159), (79), (15), (8), (7), (7), (3), (3), (3), (3), (3), (2), (2)
Host Rabbit
(104), (47), (24)
Clonality
Polyclonal
Conjugate This MAPKAP Kinase 5 antibody is un-conjugated
(7), (7), (7), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(150), (87), (40), (22), (13), (13), (10), (4), (3), (1), (1), (1)
Supplier Log in to see

Product Details anti-MAPKAP Kinase 5 Antibody

Target Details MAPKAP Kinase 5 Application Details Handling Images
Specificity This phosphorylation site is homologous to that of Thr182 in Mouse.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human MAPKAPK5 around the phosphorylation site of Thr182
Isotype IgG

Target Details MAPKAP Kinase 5

Product Details anti-MAPKAP Kinase 5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Mapkapk5 (MAPKAPK5 Antibody Abstract)
Background

Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53. Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, enabling expression of miR-34b and miR-34c, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent MYC translation. Acts as a negative regulator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB. Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4: the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4). Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stimulation, inducing F-actin rearrangement.

Subcellular location: Cytoplasm, Nucleus

Synonyms: MK5, MK-5, PRAK, MAPKAP-K5, MAP kinase-activated protein kinase 5, MAPK-activated protein kinase 5, MAPKAP kinase 5, MAPKAPK-5, p38-regulated/activated protein kinase, MAPKAPK5

Gene ID 8550
UniProt Q8IW41
Pathways MAPK Signaling

Application Details

Product Details anti-MAPKAP Kinase 5 Antibody Target Details MAPKAP Kinase 5 Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MAPKAP Kinase 5 Antibody Target Details MAPKAP Kinase 5 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-MAPKAP Kinase 5 Antibody Target Details MAPKAP Kinase 5 Application Details Handling back to top
Supplier Images
ELISA image for anti-MAPKAP Kinase 5 antibody (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5) (AA 160-210) (ABIN710546) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...
SDS-PAGE (SDS) image for anti-MAPKAP Kinase 5 antibody (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5) (AA 160-210) (ABIN710546) Lane 1: mouse lung lysates Lane 2: mouse brain lysates probed with Anti phospho-MAPKA...
Immunohistochemistry (IHC) image for anti-MAPKAP Kinase 5 antibody (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5) (AA 160-210) (ABIN710546) Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-MAPKAPK5(Thr...