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anti-Human MCL-1 antibody for Immunohistochemistry

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Reactivity
Human
331
111
73
10
9
5
5
3
3
2
1
1
1
Host
Mouse
223
97
20
2
Clonality
Monoclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
7
6
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
282
141
113
86
83
51
32
27
25
22
7
6
1
Supplier
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Catalog No. ABIN969485
$ 345.40
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.22865479 ABIN1533338 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22865479 ABIN2706515 IHC WB Rabbit Center Log in to see Polyclonal
0.22865479 ABIN2453283 IF IHC WB Mouse IgG2b Log in to see 9C9
0.22865479 ABIN2453284 IF IHC WB Mouse IgG2a Log in to see 3B4
0.22865479 ABIN2453285 IF IHC WB Mouse IgG1 Log in to see 10C5
0.22865479 ABIN2469709 IHC ELISA WB Mouse IgG1 Log in to see 8C6-8C6D4B1
0.22865479 ABIN2453282 FACS IF IHC WB Mouse IgG2a Log in to see 2E11
0.22865479 ABIN2453277 FACS IF IHC WB Mouse IgG1 Log in to see 10F6
0.22865479 ABIN2453281 IF IHC WB Mouse IgG2a Log in to see 9D7
0.22865479 ABIN2453286 FACS IF IHC WB Mouse IgG2a Log in to see 10D10
0.22865479 ABIN2453280 IF IHC WB Mouse IgG1 Log in to see 4B7
0.22865479 ABIN2453279 IF IHC WB Mouse IgG2a Log in to see 3A12
0.22865479 ABIN2448778 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.22865479 ABIN2464081 IHC ELISA WB Mouse IgG1 Log in to see 8C6D4B1
0.22865479 ABIN2470667 IHC ELISA WB Mouse IgG1 Log in to see 8C6D4B1
0.22865479 ABIN2445514 IHC WB Rabbit Ig Fraction Center Log in to see Polyclonal
0.22865479 ABIN3210201 IF IHC ELISA WB Mouse IgG1 Log in to see 8C6-8C6D4B1
0.22865479 ABIN2448023 FACS IHC WB Rabbit Ig Fraction Log in to see Polyclonal
0.22865479 ABIN2432675 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.22865479 ABIN2434308 IHC ELISA Rabbit IgG Log in to see Polyclonal

Top referenced anti-MCL-1 antibody for Immunohistochemistry

Similar anti-MCL-1 Antibodies

Application / Reactivity Human
ELISA 135 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 32 Antibodies
Immunochromatography (IC) 7 Antibodies
Immunocytochemistry (ICC) 51 Antibodies
Immunofluorescence (IF) 83 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 114 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 26 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 86 Antibodies
Immunoprecipitation (IP) 24 Antibodies
Western Blotting (WB) 276 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Reactivity Human
(331), (111), (73), (10), (9), (5), (5), (3), (3), (2), (1), (1), (1)
Host Mouse
(223), (97), (20), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(282), (141), (113), (86), (83), (51), (32), (27), (25), (22), (7), (6), (1)
Pubmed 2 references available
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN969485) Images
Purification Purified
Immunogen Purified recombinant fragment of human MCL-1 expressed in E. coli.
Clone 8C6
Isotype IgG1

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 Antibody (ABIN969485) Images back to top
Antigen
Alternative Name MCL-1 (MCL1 Antibody Abstract)
Background Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.
Molecular Weight 37 kDa
Gene ID 4170
HGNC 4170
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 Antibody (ABIN969485) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 Antibody (ABIN969485) Images back to top
Format Liquid
Buffer PBS containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-MCL-1 Antibody (ABIN969485)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Product cited in:

Richert, Schwertfeger, Ryder, Anderson: "An atlas of mouse mammary gland development." in: Journal of mammary gland biology and neoplasia, Vol. 5, Issue 2, pp. 227-41, 2001

MacLachlan, Hébert: "Statement concerning euthanasia and physician-assisted suicide. Ethics Committee of the College of Family Physicians of Canada." in: Canadian family physician Médecin de famille canadien, Vol. 46, pp. 254-6, 264-7, 2000

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN969485) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (ABIN969485) Figure 1: Confocal immunofluorescence analysis of HepG2 cells using MCL1 mouse mAb (g...
Immunohistochemistry (IHC) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (ABIN969485) Figure 2: Immunohistochemical analysis of paraffin-embedded human lymphnode tissues u...
Western Blotting (WB) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (ABIN969485) Figure 3: Western blot analysis using MCL1 mouse mAb against Hela (1), BCBL-1 (2), Ju...