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anti-Human MCL-1 antibody for Western Blotting

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Epitope
AA 217-245, Center
35
23
23
15
15
14
13
13
11
10
9
5
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
331
111
73
10
9
5
5
3
3
2
1
1
1
Host
Rabbit
222
98
20
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
12
10
10
7
6
5
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
282
142
114
85
83
52
32
27
25
22
7
6
1
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Catalog No. ABIN657627
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13476625 ABIN222889 IP IHC WB Rabbit IgG Log in to see Polyclonal 2
0.13476625 ABIN500252 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 1
0.13476625 ABIN500254 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 1
0.13476625 ABIN500256 EIA IF WB Rabbit IgG Center Log in to see Polyclonal 1
0.13476625 ABIN185242 ELISA WB Goat C-Term Log in to see Polyclonal 1
0.13476625 ABIN388105 FACS IHC (p) WB Rabbit Ig AA 191-226, BH3 Domain Log in to see Polyclonal 5
0.13476625 ABIN675369 IF (p) IHC (p) WB Rabbit IgG AA 210-248 Log in to see Polyclonal 3
0.13476625 ABIN967637 IP WB Mouse IgG1, kappa C-Term Log in to see 22-Mcl 6
0.13476625 ABIN969485 ICC IHC ELISA WB Mouse IgG1 Log in to see 8C6 2
0.13476625 ABIN967399 IHC (f) IHC (fro) IP WB Rabbit Ig Fraction AA 121-139 Log in to see Polyclonal 6
0.13476625 ABIN1533338 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.13476625 ABIN1532715 ELISA WB Rabbit IgG Log in to see Polyclonal
0.13476625 ABIN3043876 IHC (p) WB Rabbit IgG AA 1-350 Log in to see Polyclonal
0.13476625 ABIN3044422 WB Rabbit IgG AA 303-325, C-Term Log in to see Polyclonal
0.13476625 ABIN2465932 ELISA WB Goat C-Term Log in to see Polyclonal
0.13476625 ABIN2706515 IHC WB Rabbit Center Log in to see Polyclonal
0.13476625 ABIN2801930 WB Rabbit IgG Log in to see Polyclonal 5
0.13476625 ABIN2453286 FACS IF IHC WB Mouse IgG2a Log in to see 10D10
0.13476625 ABIN2453278 IF WB Mouse IgG1 Log in to see 2D6
0.13476625 ABIN2855261 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal

Top referenced anti-MCL-1 antibody for Western Blotting

Similar anti-MCL-1 Antibodies

Application / Reactivity Human
ELISA 135 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 32 Antibodies
Immunochromatography (IC) 7 Antibodies
Immunocytochemistry (ICC) 51 Antibodies
Immunofluorescence (IF) 83 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 114 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 26 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 86 Antibodies
Immunoprecipitation (IP) 24 Antibodies
Western Blotting (WB) 276 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Epitope AA 217-245, Center
(35), (23), (23), (15), (15), (14), (13), (13), (11), (10), (9), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(331), (111), (73), (10), (9), (5), (5), (3), (3), (2), (1), (1), (1)
Host Rabbit
(222), (98), (20), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This MCL-1 antibody is un-conjugated
(12), (10), (10), (7), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(282), (142), (114), (85), (83), (52), (32), (27), (25), (22), (7), (6), (1)
Pubmed 3 references available
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN657627) Images
Specificity This MCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the Central region of human MCL1.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This MCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 AA from the Central region of human MCL1.
Clone RB33638
Isotype Ig

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling References for anti-MCL-1 Antibody (ABIN657627) Images back to top
Antigen
Alternative Name MCL1 (MCL1 Antibody Abstract)
Background This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Synonyms: Induced myeloid leukemia cell differentiation protein Mcl-1,MCL1,BCL2L3
Molecular Weight 37337 DA
Gene ID 4170
NCBI Accession NP_068779, NP_877495
UniProt Q07820
Research Area Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Cell Structure, Protein Modifications, Cell Cycle
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling References for anti-MCL-1 Antibody (ABIN657627) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details References for anti-MCL-1 Antibody (ABIN657627) Images back to top
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MCL1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months

References for anti-MCL-1 Antibody (ABIN657627)

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling Images back to top
Background publications

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010

Maurer, Charvet, Wagman, Dejardin, Green: "Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1." in: Molecular cell, Vol. 21, Issue 6, pp. 749-60, 2006

Domina, Vrana, Gregory, Hann, Craig: "MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol." in: Oncogene, Vol. 23, Issue 31, pp. 5301-15, 2004

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling References for anti-MCL-1 Antibody (ABIN657627) back to top
Supplier Images
Western Blotting (WB) image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (AA 217-245) (ABIN657627) MCL1 Antibody (Center) (ABIN657627) western blot analysis in Y79 cell line lysates (3...